Kidney Disease Without Protein In Urine? Kidney Failure?


Jun 17, 2013

Is it possible to have CKD or kidney failure without protein in urine?

Last week my masseuse found a knot in my back that she suspects could be inflammation in my kidney. I've had some weird symptoms popping up over the last month like foot/ankle swelling, profound fatigue, leg cramps and blurry vision. This last week though I began developing SEVERE flank pain (like 9 on a 10 scale), back pain (started out lower, now entire back), horrible nausea, horrible headaches, shooting pains down my legs, metallic taste in mouth, dizziness and loss of appetite. Not to sound melodramatic but I feel like I'm dying. The pain is constant but the intensity seems to be moving in 24 hour cycles. Today I feel awful but I was able to shower/get dressed. Yesterday I couldn't even get out of bed. I slept for 16 hours. It's been going in that pattern for the last week and a half.

My doc did a urine culture last week, got results today and there was no protein in my urine, but I had 3+ ketones and a large amount of leukocytes. Blood work from a month ago just came in and my kidney numbers were off a month ago: BUN (32), Creatinine (1.8), eGFR (33). Between the symptoms and the blood test I'm thinking it sounds like renal failure, but could it be CKD without protein in the urine?

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I was just wondering if anyone has protein in their urine with Chronic Kidney Disease and what did your doctor do about it if anything.  I am trying to keep my GFR stable.  The last time it went up a bit but am worried about the protein causing more damage quicker.

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Kidney Disease :: Hematuria And Protein In Urine

For the last five months I have been experiencing blood and protein in my urine. After a very thorough assessment from a urologist everything came back normal. I was referred to see a nephrologist to see if the blood is coming from my kidneys. my kidney panel came back normal except for lower than normal creatinine levels???? but my urinalysis came back all wrong. It's showing 3+ for blood, 100 mg for protein, 1+ bilirubin, urine color is brown, ph of 5.5.

The dr also order a ANA test to check for lupus, but it came back negative. I'm completely lost, can a person have kidney disease w/normal kidney function?or lupus nephritis w/negative ANA test?

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I'm a 37 year old female, 2 years ago at the Birth of daughter I developed severe preeclampsia, and went onto develop pregnancy related heart failure - post Partum cardiomyopathy. I nearly didn't live, but I'm lucky to have recovered full heart function and my heart is now considered normal.

I've known since having the preeclampsia of protein in Urine causing a foamy appearance, I still have this now, and had been testing my own urine with dipsticks over the last 2 years ranging from plus 1 to plus 4 throughout the day. Virtually all morning samples negative.

Last year I was tested at my GP office and an ACR which came back at 98mg. At the Time my GP said re test in 3 months and suggested it still might be my body settling down from the heart failure etc, I continued to test myself and never want back to the doctors because basically I wanted to forgot about illness and live life without worry bringing my daughter up. Now another year later my urine was getting even more foamy, I decided to go back to my GP, I've had the following tests and have been referred to a nephrologist which isn't until the end of September:

eGFR: over 90
ACR: 198 mg
Protein in blood: Normal
ANA: normal ( i have had previously positive ANA two years ago)
FBC: all normal
ESR: Normal
Liver function test: Normal (I also had trace Bilirubin in my urine)
Glucose: Normal
Kidney & bladder ultrasound: Normal
24 hr urine: 0.3grams (300mg)

I know I have been spilling the protein since the preeclampsia, sometimes I have tested my urine all day and it has been Plus 4 for each one, so I'm guessing tallying this up must be well over 2000 mg a day, when I did my 24 hr there was only one urination that showed a plus 3 on dipstick that day which correlates to the 300mg reported over 24hrs

I have low blood pressure naturally 100/60, I'm off all heart medications, I healed quickly and came off them after 6 months of heart failure. I'm not diabetic, it doesn't appear I have any autoimmune disease such as lupus, all my bloods are normal, so is my kidney function, yet I'm still passing quite high amounts of protein.

I know only a nephrologist can help determine what's going on, but my appointment is not until the end of September, I do a lot of googling (too much information i know can make things worse!) and know that protein can continue to make the kidneys worse, I'm concerned there is an underlying condition, and even if its primary how quickly can this progress with high levels of protein? Could I get acute kidney failure? My mother has stage 3 CKD for years and passing no protein, however she is on ACE inhibitors. My GP said I will probably go on these, I was on these for my cardiomyopathy and preeclampsia and once my blood pressure returned to normal I had to come off them as I was very dizzy and light headed. So although they may help kidneys, I'm concerned I won't be able to tolerate them.

Also what could be causing this? primary glomerulonephritis? Could the preeclampsia heart failure have caused permanent damage and hopefully now my heart failure is better no more damage will develop?

I have no other Symptoms at all, all this came about because I noticed my urine was still foamy.

My biggest concern is that although my kidney function is still normal, is it possible it could decline rapidly because of the protein?

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What is the normal range? What is considered really bad vs just concerning?

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I'm hoping that someone can help to alleviate my severe stress level. For my annual checkup a week ago, I had a urinalysis done. This is the first time I've had this done, as I have a new doctor. The results showed that I was a 1+ for protein. Specific gravity was 1.015 and everything else was negative. There were no red blood cells, no white blood cells, no epithelial cells, no bacteria, no crystals, and most importantly no casts. The one very strange thing was a PH of 8.5, which seems way out of wack. I took my PH here at home, and it's around 6.0. I have read that a high PH can cause a false positive for the protein. So, my doctor said that he wanted me to come in to have it checked again. In the meantime, like an idiot, I went searching around on the internet about chronic kidney disease. So, I was freaking out for almost a day, and gave my second test the next morning. However, when I urinated in the morning, the water in the toilet foamed up like a mug root beer! Then I REALLY started freaking out, reading that foamy urine means protein in the urine. I do NOT remember seeing foam in my urine before this. I do have a long history of anxiety and panic issues. I do NOT have a history of chronic hypertension. If I'm at the doctor's office, or times when I'm anxious and panicky, my blood pressure can get above 140/90. Most of the time it is below 130/90, and I can get it to 120/80 or lower when I'm completely relaxed. My prior doctor almost always told me 120/80 when I was in for checkups. Also, back in November I had blood work done, and that showed that my creatinine level was on the high side of normal (1.19), but still in normal range, and I have no idea if I exercised the night before, ate meat, etc. More importantly, my blood albumin level was right in the middle of normal at 4.4, and total protein was also in normal range, and my BUN was 15. I have read that stress can cause there to be protein in the urine, and I'm REALLY hoping that is what is causing what I'm seeing, because everything else seems to look good in the tests, especially that there were no casts found. One further thing...there was ONE time since I had the second test that I had a long stream of urine, and there was NO foam in the water...completely clear. This was after I had spent some time with a friend and was fairly calm. However, every time since then...the last 2 days...foam every time. I'm to the point where I'm not even looking...just turning my head away. I'm hoping that someone else has had a similar experience and can tell me that there is a chance the foam can be caused by my stress level, and that I just need to calm down and relax since all the other tests look good. I have some hope because of no casts being found, and because of the prior blood work and the one time I urinated with no foam.

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can take enalapril or losartan? will it affect or worsen kidney function.

well, i have been taking enalapril since 2008 . my creatinine was hopping around 150-180 in these 7 years till 2015.

However, due to chronic diarrhea , vomiting. acute renal failure. creatinine shoot up to 400 in Jan and urine infection in march.

creatinine now hopping around 200-250.

doctor stop my enalapril and replace with amlodipine 5mg

once i stop the enalapril , my urine protein is back. from march 0.17g to 0.61g. i am worried.

i didn't have any urine protein over those few years since 2009 to 2015. i guess this is the reason which i can keep well in my condition with creatinine hopping around 150-190.

i am worried that the urine protein my cause my kidney worsen and dialysis may starts soon.

Posts: 11

Joined: Tue Apr 19, 2016 5:03 am

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however, last few days, my creatinine shoot up to 240. such a shocked to me. as i didn expect there is so much shoot in just few weeks time.

doctor has been stop my enalapril, which i used to protect kidney and keep my urine protein negative.

however, there is 1+ urine protein in my urine test. my blood pressure used to below 130/80. now sometime, it can shoot up to 150/95 if i do some physical activity.

i have been worried for my condition. This year, i was admitted twice. Jan admitted due to diarrhea and dehydration. delay the admission. so creatinine shoot up to 400++, nearly need dialysis. however, after drip. then able to drop to 150++

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1.8x1.8x1.7 cm left parapelvi lesion which appears to have a thin septation which is traversing blood vessel. Precontrast density of the cystic portion was 7 hounsfield units and postcontrast density of the cystic portion was 4 hounsfield units.  Precontrast density of the septations was 14 Hounsfield units and post contrast CT density of the septation was 37 hounsfield units. 

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