High Dose Of PPI - Barrett's Oesophagus


Sep 15, 2007

Hi, have just read your interesting comments. my son who's 21 is awaiting biopsy results, he's been told its probably Barretts. So i'm just trying to find out all the info. he's been told to commence on high dose of PPI, i just hope there's no complications.

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Barrett's Oesophagus :: Do's And Don'ts ?

This is my first posting to the Barrett's Oesophagus group, having just been diagnosed with Barretts and a Hiatus Hernia on my Birthday (what a birthday present). I am amazed at how quickly the symptoms have arisen. Suddenly I can eat very little (both in quantity and variety) and trying to find my way around what I should eat, drink etc. I feel left in limbo by my consultant and GP, who just said I would have an endoscopy every 2 years, and that I needed to manage it well or it could lead to cancer, a bit worrying when they are not advising me what I should do!

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Barrett's Oesophagus Has Increased?

A recent study showed 20 years on most patients' Barrett's segment lengths remained the same as at initial diagnosis.

Thus it was with some confidence I approached my surveillance gastroscopy yesterday that my 3 cm circumferential band of non-dysplastic Barrett's would show no changes.

Awake throughout the rather longer than usual procedure (unfortunately sedation has no effect on me), I listened to the doctor call out the distances to her recording nurse as she took 20 biopsies and realised this was longer than 3 cm.

"8 centimeters", she confirmed when I asked her afterwards. ""Full circumference lower down and patchy higher up."

I was astounded. With my Nissen fundoplication years ago and the Collis-Nissen revision last year reducing reflux, I hadn't expected that.

It took my wife to unravel the blindingly obvious.

"Doesn't the Collis procedure lengthen your oesophagus?"

"Yes."

"And what constitutes that increased length?"

Of course. The extended oesophagus is lined with gastric cells. And the length of that extension? - About 5 cm.

The biopsies for the bottom 5 cm will show gastric cells which, depending on histopathology, may be interpreted as gastric metaplasia but not intestinal metaplasia.

I feel sure my previous 3 cm of non-dysplastic Barrett's remains unchanged but has 5 cm of stomach cells lining the extended oesophagus below.

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Barrett's Oesophagus At COM2?

I have recently been diagnosed with Barretts at COM2, what does that mean?, i have had 4 lots of tablets so far with dreadful side effects, so soon to be given another one to try,worried as i keep being told i need the tablets to help me.

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Just Diagnosed With Barrett's Oesophagus

After having reflux and pains in my throat and stomach for a long time my GP finally referred me for a Endoscopy in January. The Doctor carrying this out said I had Barrett's Oesophagus and showed me some pictures. It is rather scary just how red and inflamed it looked. He asked me what medication I was on and I said Omeprazole (20mg) twice a day but I needed to take Rennies antacid tablets (orange) as well to help with the discomfort.

The Doctor told me to keep on with the Omeprazole as it is a precancerous condition and this would help. He also said I needed to have a endoscopy every three years. I am finding that the omeprazole doesn't help when I have the discomfort and the only relief I can get is when I take the Rennies and sometimes Gaviscon. I am still taking the omeprazole as instructed (40g a day) but wondered if anyone else who suffers with this finds omeprazole ineffective or takes something else as well. I'm sure the prolonged taking of Rennies isn't good. 

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Barrett's Oesophagus :: Pain Ever Since After Endoscopy

I had an endoscopy in February to assess why I had a lump sensation in the throat and some stomach pain. Prior to the procedure I had no chest pain whatsoever. 

After the endoscopy, I was diagnosed with silent reflux and Barrett's Oesophagus and have had chest pain ever since.

I told the consultant about this a few days ago and he wants to perform another endoscopy to find out why I have had chest pain since the initial procedure. I'm a bit hesitant as I'm not 100% sure that he didn't cause the problem in the first place. Would anyone else go ahead or get another consultant to have a look?

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Barrett's :: Damage To Duodenum And Oesophagus

I was wondering if anyone can shed any light for me I had an endoscopy on Monday just gone where biopsies were taken so I understand I need to wait for those , my doctor stated I have severe damage to my oesophagus and mild damage to my duodenum bulb and said he will tell me more when biopsy results are back. However being very curious I've obviously read his findings in the pack he sent away with me, the bit I need help understanding is in the diagnosis it states Barrett's oesophagus fold starts at 36 cm c5m3.

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Barrett's Oesophagus :: Radiofrequency Ablation With Displacer

My husband is having Radiofrequency ablation tomorrow and we are both very worried about it and hope it's going to be a simple operation but worried how he will be after for eating as he has lost a lot of weight already has anyone else has this treatment done...

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Barrett's Oesophagus :: Coughing Up A Lot Of Phlegm And Mucus

But I don't know if this is connected but for the last month I have been very chesty and coughing up a lot of phlegm and mucus

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Barrett's Oesophagus :: Pain In Neck When Eating

Just wondering if anyone else has experienced similar, I have Barrett's Oesophagus and a hiatal hernia, recently I've been experiencing pain in my neck while eating and just after, also bouts of hiccups that I haven't had before?

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Barrett's Oesophagus :: Lansoprazole - How To Relieve Burning Effect In Throat?

I have been diagnosed with Barrett's Oesophagus and am being treated using Lansoprazole tablets. My question is how does one soothe the burning effect in the throat?

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Getting Off A High Dose And Long-term Use Of Fentanyl ?

I have been on the fentanyl patch for over 15 years for neurogenic pain associated with MS.  I have decided I would like to decrease my dose from a 100 mcg patch every 48 hrs to every 72 hrs, but I am having very little  success.  The withdrawal symptoms I experience are just awful, I get just horrific leg cramps that I cannot control, they are just a nightmare, so painful that I cannot describe them.  I get the stomach problems and tiredness and constant yawning, those I can basically deal with, but the leg cramps are so hard to tolerate that I change to a new patch as soon as I feel as if they are about to start.  It is hard to believe that aI get such bad withdrawal symptoms from just trying to add 24 hrs to each patch!

I am also very tolerant to the drug. A surgeon tried to use it for anesthesia for a simple procedure and it did not phase me at all, so I was awake through the entire surgery.  They gave me so much trying to put me into a "sleepy state" that I ended up staying in the hospital overnight because they were worried about the amount they ended up putting in me.

Is there anyone out there that has successfully gotten off a high dose and long-term use of fentanyl?  I am really regretting that I started to use it in the first place, but it is the only thing that has really helped my pain and allowed me to continue to work and drive and not be all "stoned".



Anyone with any comments or solutions I would love to hear from you!

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Polymyalgia Rheumatica And GCA :: Should I Start High Dose Prednisone?

I have had jaw aching and painful to open wide for 2 days. Just on left side. No headache except I did wake up this morning with both eyes aching around the rims. No other symptoms.

I've just re-watched the Youtube of Prof Dasgupta talking about the symptoms and how one problem is patients themselves not referring themselves in time and how some people don't even recognise jaw pain as a red flag symptom.

The question is, should I get myself to A&E (which seems to me to be over the top ) and start 60mg Pred right away???

I keep thinking that it's probably something simple - but should I be taking action?? I don't want to go blind.

Do you always have systematic symptoms as well like fever?

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Sertraline :: 50mg Dose To 200mg Dose - Pros And Cons?

I have been on Sertraline 50mg for 6 weeks, I saw my therapist and she asked how I felt, I told her I did not feel any different, she contacted my Dr. and the Dr. upped my dose to 200mg, this has frightened me, a leap from 50mg to 200mg, has anyone had this outcome, and what were the pro's and con's of this sudden higher dose.

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Rabies Vaccine Dose - 6th Dose Is Optional Or Mandatory?

In Ukraine, the dog has bitten me. At the end of treatment, 6 doses of rabies vaccine is recommended in the report. They make 4 dose in Ukraine and I come to my home (Istanbul) and 5. dose is finished. But total five doses of vaccine are made in Turkey. I do not understand why they want to dose 6. I have a healthy body. 6. dose is important? OR optional?

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Barrett's Oesophagitis :: Sore Throat With Bad Cough

Have barrett's esophagus.

Ibs.acid reflux.

Asking for bit of of help or advice.

I always have a really sore throat and a nagging cough. I always feel really run down and feel like crappie . No energy. Like flu symptoms. Always have bad stomach . Back ache . All in all I feel unwell everyday .

I have been on 40 milligram of omeprazole for about 6 years or so . But I don't no if they are working very well .I am due a scope in early summer I think .
And do people no if being on ppi for long can affect me.

Also I am lactose intolerance .so I only have a little bit of soya milk each day .

My throat always feel like it closes up and goes very red .

Bit worried and would like to feel healthy for once as I am only 29.

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Throat :: Hollowness In Upper Oesophagus

Hollowness in upper oesophagus?

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Reflux Oesophagitis :: Thickening Of Lower End Of Oesophagus

I have had problems with severe pain on eating and drinking for the past 7 months and have had treatment for gastritis and 2 weeks ago I had my gallbladder removed. After the operation I developed serious acid reflux which progressively got worse and alongside the difficulties eating and drinking landed me in hospital a week ago. Today I had a ct scan which revealed a thickening of the lower end of my oesophagus. I am in pain now day and night and pain killers not that effective. Pain radiates through from front to back between shoulder blades and keeps me awake at night. I now need an endoscopy to determine what the thickening is and I am really worried that it is something sinister. CT scan sword everything else to be normal. I'm on 80mg Omeprazole a day in two doses and 600 mg of Ranitidine and I feel terrible with the side effects. The acid reflux settled to some extent in about 3 days but the pain is no better and I'm losing weight because I can't eat. As I'm in hospital the endoscopy will probably take place over the next couple of days but I'm worried sick as to what they will find. Does anyone know what thickening of the oesophagus means in association with my other symptoms.

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Esophageal Achalasia / Spasm :: Botox Injections Into Oesophagus

After 15 years with Achalasia and difficulty with food passing into my stomach I finally had Botox injections yesterday. During the endoscopy the dr said the valve at the bottom of my oesophagus was really tight and he's hoping the Botox will help me.

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Hypertension :: High Carbohydrate Food Causes High Blood Pressure (100/170)?

i am not overweight. Drink a healthy smoothie and whole grain cereal almost every morning yet my BP is still high. (100/170). I was  told it may be because of elevated insulin levels caused by the fruit drinks and whole grains (as well as the potato, rice, pasta and breads) that I eat. These are things that easily break down into sugars and cause the issue. (Basically a carb issue). Am I supposed to go on one of those caveman diets? Has anyone tried lowering their carb intake to lower their BP? 

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GERD (acid Reflux) :: Constant Belching And Tight Oesophagus

I was wondering if anyone can confirm these symptoms...I'm currently seeing doctors about my GERD issues, but I kind of feel like I'm alone in all this.

My issues:
1. Belching
2. Flatulence
3. Regurgitation
4. Tight feeling in throat and oesophagus
5. Stomach cramps
6. Small hiatal hernia

Basically, for the last couple of weeks I've felt really horrible. I get these bloating pains and some days I'm constantly belching. Along with the belching, my oesophagus feels tighter. Having a lot of flatulence as well.

The thing about the belching, it doesn't feel like normal belching. When I belch, I feel this ripple like sensation through my oesophagus. I'm currently on my first week of Dexilant and have quit smoking as of last week. I avoid all standard GERD triggers, and I'm just hoping this gets better soon. This really doesn't feel like living!

Does anyone else get the belching I mentioned above? I find it hard to believe it's my diet, I barely ate today and I've been getting these painful burps all day!

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