Transplants - Sirolimus :: Creatinine High - Level Is ~1.7 For Last 1.5 Year
Sep 20, 2014
I have completed 3yrs after liver transplant. My creatinine level is ~1.7 for last 1.5year. Prograf dose is reduced to 0.5mg BD, and tac level is 6.3. Mycophenolate can not be used because it causes leucopenia.
Doctor is thinking to switch to Sirolimus. But with Sirolimus I see this warning.
The safety and efficacy of Rapamune (sirolimus) as immunosuppressive therapy have not been established in liver or lung transplant patients, and therefore, such use is not recommended [see WARNINGS AND PRECAUTIONS].
Liver Transplantation – Excess Mortality, Graft Loss, and Hepatic Artery Thrombosis (HAT)"
Do you think it is safe to use sirolimus?
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Hi my creatinine level jumped from 1.5 in Jan 2014 to 4.29 in July 2014. My legs and feet suddenly started swelling and I urinate frequently. Since all this started,I'm also thirsty all the time. Also, I guess it's pertinent to mention that my mother (73) just started dialysis, which she does at home herself. My daughter is now on the kidney transplant list, she's 30, but hers is attributed to Graves Disease, I believe. Is Kidney issues hereditary? .
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My doctor sent my test results. He highlighted Creatinine 1.13mg/dL HI. My GET is 58 no/min/1.73 m2
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I had some blood work done last week any my Creatinine was 1.15 and my GFR was 57. I know these aren't alarming numbers necessarily, but 6 months ago my Cr was .72 and my GFR was 100 so it's a huge change. Everything else (BUN, BUN/CR ratio) were normal. Doctor was unconcerned and wanted to check in 3 months. Anybody have any thoughts on this? I do take lots of supplements but have taken them for years with normal kidney function. Also have taken a lot of Benadryl lately. I'm stumped at this big change. Also I am not diabetic and do not have high blood pressure.
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I have never had any issues with my kidneys other than a few kidney stones,,and pretty frequent uti's..like bladder infections. I went to my primary care provider in mid December and she did bloodwork. It was done 12/18. My eGFR is 23!! And my creatinine is 2.26. I have an appointment with a nephrologist on Tuesday and I'm just worried. My only symptom is that I wake up slightly nauseous almost daily. Anyone she'd any light on this?
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I am diabetic patient for past 6 years. Presently I am taking medicine ZIGLIM M1 in the morning daily after breakfast. I checked my sugar level 2 or 3 times, the value of FBS level was 120 mg/dl and RBS level was 210 mg/dl . My RBS value is always high
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The doc put me on niacin to lower my cholesterol I haven't taken it yet scared it may mess with me but my question is will high cholesterol cause vision issues and other side effects
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I have been taking Zyloric 100 for the past couple of years, Uric Acid level was 7.5 prior taking medicine, but during taking medicine it was 4.5, my question, should I continue taking Zyloric, though I never suffered from severe illness, like toe inflammation.
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My husband is 80 years old and has type 1 diabetes now it is found to be difficult to control his blood sugar level especially at night. when he goes to bed, sugar level is 17 mmol and in the morning his blood sugar level has dropped to 3 mmol. This problem occurs only in night time.
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I had a my uterus removed because of problems, they do transplants on just about every organ. How about a uterus? I really want a baby with my husband.
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I had a blood test around 7 months ago which showed my blood sugar Hb1AC to be close to pre-diabetic levels, which freaked me out. My cholesterol was also a little high.
I cut down on sweet things (which I love!) a lot, and had my blood tested again a few weeks ago. good news is that the blood sugar levels have dropped, triglycerides low, liver function great. HOWEVER, my cholesterol has leapt to 6.6! So annoyed!
The nurse quizzed me on my diet and the only thing we can pinpoint is that I eat a lot of cheese, so have started eating low fat cheese or not eating as much in general. I generally eat what I consider to be a healthy diet, oily fish, veg, etc but not sure what to believe.
I read that a high fat diet is now the way to go with low carb, but whilst this seems to have helped with blood sugar, it has not done my cholesterol any good.
I have to go back in 3 months. Anyone else had this type of result?
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Are these two tests the same thing? Also, we are having trouble reading my mother's blood tests - and yes we have an upcoming appt but the office is very busy. She has a Protein/Creatinine ratio of 4.75. Her U creatinine is 60 and her protein is something like 13.
There isn't a normal range for the Protein/Creatinine ratio, though I know in the past it's been something like 0.83. Her blood creatinine was steady for her ... 1.9 and her GFR steady for her at 28. So...I don't get how the protein can be so much higher than it was before.
Every time I look up protein/creatinine ratio - I keep getting "albumin" results. Is this the same test?
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i am not overweight. Drink a healthy smoothie and whole grain cereal almost every morning yet my BP is still high. (100/170). I was told it may be because of elevated insulin levels caused by the fruit drinks and whole grains (as well as the potato, rice, pasta and breads) that I eat. These are things that easily break down into sugars and cause the issue. (Basically a carb issue). Am I supposed to go on one of those caveman diets? Has anyone tried lowering their carb intake to lower their BP?
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Let me start off by saying I am a 20 year old male who was fine before all of this started. I went to the ER for chest pain and palpitations they did the basic test like EKG Xray and Blood work. The ER doctor said i was fine and they let em go home but said i need to see a cardiologist to just make sure everything was fine. So i went to see a cardiologist and the hospital faxed over all of my test results. Based on my ER visits EKG i have an abnormally high P wave everything else on the EKG was fine. They set me up for a Echocardiogram to make sure i did not have an enlarged heart. that test came back normal and they said i did not have a enlarged heart. They set me up for a Stress Echo test I went in for the test got my heart rate up to 200bpm the before and after pictures of my heart looked good and they said everything was working fine and that i was healthy. But during the test i still have those high P waves showing up on the EKG which he said was caused because I am very thin chested and my hear beats close to the surface of my chest so the EKG pick up a higher voltage. Now i have noticed a slight arrhythmia when i take my pulse it tends to beat at 60 bpm then 5 or 6 beats later it jumps to 80 bpm then back to 60 after 5 or so beats. This comes and goes and does not happen all the time and when it does happen it only last up to 30 minutes but during that time i feel fatigued . And finally my blood pressure seems high the systolic pressure is always within normal range its the diastolic that always above normal when i tested my blood pressure with a home blood pressure monitor today it was at 135 over 87 then when i tested it later on in the day it was 127 over 83 i have noticed in multiple test the diastolic seem to float around the mid 80's to 90's the highest i have seen is 133 over 99. The cardiologist does not see to think there is anything wrong with me I have another appointment this week to bring up the high blood pressure and the arrhythmia.
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Hi, Is is possible to have a high heart rate while at the same time a normal rate of blood pressure? I'm asking on behalf of a relative... I thought blood pressure would be high if the heart rate was also high?
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My mom was having problem with vomiting for like 3 years.Anything she ate she vomited.This had up and down intensity. About 6 month ago we saw a gastronomy dr and he did endoscopy and the result showed h pylori. he did not prescribe antibacteria right away.Instead he prescribed among other medicine Domperidone BP 10 mg to stop the vomiting .After a month he gave pylocure (AMOXICILLIN + CLARITHROMYCIN + RABEPRAZOLE) for 14 days.My mom did not take them then.Then one day she had chicken wings at night and blood showed up in stool the later morning. We took her to doctors and did a colonoscopy, it showed she had polyp and ulcer. This time we finished the 14 day triple therapy and she ate according to a chart i made,no oily or spicy food or fatty food.Yesterday we did another endoscopy and it showed the bacteria was gone,at least I think so as the result shows everything normal. But mom was very weak and throughout the 14 days she was taking the antibacterial she had been vomiting only water. Her mouth tasted bitter. She stopped taking anti bacteria from yesterday and no more water vomiting till now. She was very weak and we admitted her to a hospital. The dr did some tests and it showed she had Creatinine at 4.1mg/dl . She also had low sodium and dr said to take table salt.
She has been taking for diabetes and other problems like :1.oramet 850 mg( Metformin hydrochloride 850 mg)
2.osartil 50 Losartan Potassium USP 50 mg
3.Mecolagin Chewable Tablet: Each tablet contains Mecobalamin INN 0.5 mg.
4.Jointec Max is a combination of Diacerein and Glucosamine for the treatment of osteoarthritis and joint pain.
For h pylori and vomiting:
5. pylocure (AMOXICILLIN + CLARITHROMYCIN + RABEPRAZOLE) she stopped that now
6. omidon(Domperidone BP 10 mg)
After dr saw the creatinine level, he stopped Mecolagin and gave another chewable tablet Simethicone 40 mg
Now she is taking :Simethicone 40 mg,oramet 850 mg, Domperidone BP 10 mg,table salt
Dr also gave her Emistat 8 mg injection and Esonix 40mg Inj yesterday only.
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So I'm a little worried only because I'm a worry wart. I got my blood results back from the doctor today and was emailing him and he says I have nothing to be worried about but this is the first time I've ever felt like I need a second opinion with him. When I reviewed my results the only items that stuck out to me was that my Monocyte was 7.2, BUN 23, and the one that worried me most of all was my BUN/creatinine was 38.3.
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I'm a bit alarmed. I just had my 3 month check up with the doctor. I've never had any kidney problems before. My Creatinine is 2.0 and my GFR is 34. I am recovering from some major oral surgery right now and I haven't been able to eat as I normally do. Less food. I was wondering if this oral surgery and my diet could have anything to do with my test results? My doctor wants me back in his office in 6 days to discuss this test. If you have anything to share, that would be awesome!
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My creatinine just found that 1.66 what's problem how long can I live
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I am 35 year old unmarried female, i am 5feet 2 inch and my current weight is 63 kg/ 140 lb after one year dieting started when i was 77 kg.I have high cholesterol and high LDL issue in genes (my father had high cholesterol with high bp issue). My Blood pressure is normal, My cholesterol was 207 mg/dl, LDL = 160 mg/dl and HDL= 40mg/dl from 2011 to june 2015 with few up and downs but in reports of oct 2015 and march 2016 my cholesterol is increased up to 260 mg/dl, LDL = 198 mg/dl, HDL=51mg/dl, triglycerides = 100 mg/dl ,my other results are
Liver function test result are ALT/SGPT = 16U/L, SGOT = 19U/L, alkaline phosphate = 114 U/L , i am vitamin D deficient. march 2016 current level of vitamin D(25-OH) =26ng/ml . i take 600000 IU two injections in 2013 when my level was 4ng/ml and then i take 200000 IU one capsule in oct 2015 .
My prolactin level is also high since 2002 means between 75 to 100 ng/ml
My menstrual cycle is also irregular means come with gap of 40 to 70 days.
kindly tell me why my cholesterol and LDL is high if SPGT/ALT is normal. Since august 2015 i limit my whole day oil consumption is olive oil two table spoon in a day and one table spoon purified butter in a day. once in a week i eat one dunkin donut, 250 gram yogurt . i eat one egg daily.
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Recently been diagnosed with high cholesterol along with my high blood pressure. Was on atenolol and bendrofluazide but these weren't keeping my bp down so was put on lisinopril. I have had pains in my stomach since i started my new meds wake in the night with a jolt, am tired and feel weak all the time, i'm only 43 and not over weight. Has anyone else had these symptoms. I'm unsure what is causing what as every thing has changed all at once?
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