Side Effects :: Topamax - Compromised Liver Function?


Aug 30, 2015

I am a 30 year old mother of two and I've been a migraine sufferer since I was 16, where this used to be occasional a few months ago they became more frequent, occurring about 3-5 times a month with headaches in between. Up until this point in my life I never felt the need to be on any kind of medication for them, at this point I was desperate. I was popping Excedrin, Ibuprofen, Tylenol, Advil, whatever I could get my hands on just to function. After a trip to the ER to receive a nice little "migraine cocktail" to relieve my pain, I scheduled a visit with my PCP who sent me to a neuro.

This is my second trip to a neuro. Two years ago, I had an incident where out of the blue, my speech became garbled, I couldn't make any sense out of what I was saying and moments of my memory were erased. I was sent to a neuro then too (a different one) by the same PCP who did a quick little physical to be sure I hadn't had a stroke and sent me on my way. At this appointment, the doctor attributed my migraines to stress given I'm a single mother, prescribed me Topamax in addition to Imitrex to take PRN. She started me on 25mg to take twice a day for two weeks. After two days I started noticing weird side effects, tingling down my left arm and feeling like I didn't have full control of the arm. My index finger would move by itself, twitching (which is frustrating when you have to type for a living). The next side effect was my inability to form a sentence, again, very frustrating! I knew exactly what I wanted to say but for the life of me could not spit it out! I called the doctor's office, the doctor was out but they said they would relay the message and call me back. When they did they said she wanted me to stay on it but take it at night to reduce the side effects. Two weeks later it was time for me to double my dose, now I was taking 100mg daily.

I have now been on Topamax for a month and I am having tons of bruising on my arms, legs and hips with no explanation, hair loss and today I noticed my eyes are yellow. I went to E Care and they are running tests on my liver functions and have ordered me to stop the medicine cold turkey, hoping for no bad side effects of that because I can't take any OTC medications.

Has anyone else experienced liver damage from Topamax?

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