Oxycodone Side Effects - Muscle Weakness And Fatigue
Dec 22, 2013
I have a friend who has been taking oxycodone 5/325 3 a day for about 2 years without issues for severe back pain.
Recently he has had a big problem with muscle strength/weakness exercise intolerance and fatigue. He has been to physical therapy with no improvement.
Could this be from using the medication for so long, has anyone experienced such a thing.
He has been tested for MS,ALS and is now seeing a Neuromuscular specialists.
Any thoughts would be appreciated
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After seeing my GP and a specialist about ED, they've prescribed me 5mg cialis to take every day. I'm on day 3 and i'm getting side-effects, flushing (warm feeling in the face), muscle aches and also feeling fatigued and drowsy.
Has anyone else here taken it daily? do the side effects wear off or is this what I should expect now? if they wear off, i can tough it out - but if this is just how-im-going-to-feel-now.
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This adventure started about 9 months ago. Instead of my normal routine of get up, eat, hygiene, off to work (I was a remodeling contractor), I started falling back to sleep after breakfast. I must pretext this by saying that I take 40 mg of Adderall in the am and the afternoon. First it was 1/2 hour and eventually 3 hours. Then it was an afternoon nap also, Then an evening nap. This was not every day but most days. About eight or so weeks ago, I developed a blood clot behind my left knee and several in my lungs (as a result of being on my knees for long periods of time installing floor trim we figure). After I got out of the hospital, I started a slow but sure incline in my energy level. Then on October 23 (my 40th birthday) I got short of breath, disoriented, incapable of making clear decisions. eventually I called 911 and when the EMTs got here I had a blood O2 level of 89%. They took me to the ER in a bus and I have never been the same since. I have experienced no increase in my energy level, I have a sore throat most of the time, flu like symptoms, muscle weakness, Most days my mind is still strong but not all, I am functioning at about 25% of what I used to be capable of, I have problems pulling the proper word out of my brain (sometimes 8 or more times per day), I feel run down especially the day after I over do it, at least 4 people have recently tried to talk to me about conversations that I have no memory of, my allergies are not only out of control they are the opposite of what I usually experience (instead of a dry nose I now have a constantly runny nose and I sneeze 50 times per day. I did test positive for Epstein-Barr exposure at some point in my life. I have 6 of the eight symptoms for diagnosis and like 25 of the 35 or so that people with CFS report. We have not yet ruled out MS, Lupus, and all of the kinds of cancer that are required for a CFS diagnosis, but I am almost positive it is CFS. Thoughts?
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I'm feeling alone and not sure who to turn to ask and feeling like no one quite understands. My main concern is that sometimes when I get muscle weakness and feel tired, I start craving to eat and I can't stop myself even if I have already eaten well. Yesterday evening was the perfect example, Having eaten a full meal with vegetables, rice, noodles and chicken, I then followed it with a bowl of fruit with yoghurt. Very healthy, should have been enough. I then had a bowl of cereal with milk, handful after handful of cereal from the cupboard and other food I could lay my hands on. I managed to stop myself when the feeling of wanting to eat spoonfuls of sugar and golden syrup and sweets and chocolate out of the cupboard. I think felt overwhelming tiredness and ended up lying down unable to move all evening eventually falling asleep.
Today I am so shattered, I feel weak, tearful and tired and I have just been eating and eating all morning. I can't cope.
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I'm trying to be diagnosed, my doctor is that loss, extreme muscle fatigue for 2 1/2 months and now I started twitching. Of course I am freaking out I could be ALS, I feel always exhausted as if a truck as one over me, I soon as I come home from work I have to take a nap, but Dr. mention CFS but he's very worried about the twitching , Any of you have CFS with twitching of the muscles?
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About 10 days ago, I began to feel little prickly feelings, like a light needle poke, in random places on my body. I was a little concerned but figured it would go away. After a day or 2, I began experiencing a little muscle cramp in my left and right legs but my cholesterol and blood had just been checked so I called my doctor's office to find out if it might be a blood clot. They told me there were no blockages (they had just done a routine cholesterol test on me about a week before). Another day went by then my muscles began to get sore and my joints were popping sometimes. My muscles in my legs, arms (mildly), around my ribs (sometimes) and my under arms (sometimes) felt sore. I used a heated massaging pillow to make them feel better but was perplexed as to why I was having these aches. Sometimes I felt an arthritic ache also like the pain might have been in my bones. I was also having mild dull headaches. Then came a day when I felt extremely fatigued and so after a couple of days I went to the doctor. She said she was thinking I might have anemia so she had me go to the hospital and get a CBC test, a CPK test and to have my thyroid tested (I have hypothyroidism which I take medication for). The day I had my blood work done (yesterday) I felt very fatigued and was asleep by 9:00 pm, which is very unusual for me. I didn't feel muscle pain just weakness sort of. Today I feel a little muscle pain but not much, but I do feel a little weak. Also I had been having panic attacks a few times during all of this. I called the doctor's office today and the nursing staff told me the results of the blood tests from yesterday morning were all normal. I had thought it could be anemia which at least then I would have a diagnosis and could be treated but now I am even more scared because I don't know. What could this be?
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I have been having a slew of health problems recently but am still awaiting further testing. In the meantime, I am very stressed and having a hard time managing. I keep getting worried that my symptoms could be onset of ALS despite knowing how illogical it sounds. I am a 25 year old male.
First, I was diagnosed by my doctor with a sinus infection, although it was probably very slight. She prescribed me Augmentin and I took it for 5 days and immediately started feeling bad on it. After I quit taking it, I noticed some tingling in my hands and feet at work on Thursday the 11th. The next evening, Friday, my legs started to feel unsteady and heavy when I walked and my hands and arms remained tingly and had perceived weakness. On Monday morning, the 15th, I went to the ER and they believed I had Lyme Disease and prescribed me doxycycline. I took this for 7 days, but did not feel any better. I remained having perceived weakness primarily in my legs accompanied by muscle tightness, muscle soreness, and very slight, sporadic twitching all over. On the 19th, I saw a neurologist who dismissed my symptoms as not serious as my reflexes were ok (knees were slightly weak, but I was very tense during the test) and I was able to walk normal, it just felt strenuous. My lyme test came back negative and a second western blot also came back negative.
Currently, I continue to have all of my symptoms, including perceived weakness, muscle fatigue, soreness, tightness, and twitching. Symptoms are present all over my body, but concentrated in my legs. When I lay down at night, my whole body will feel as if I had a sunburn and I am having difficulty sleeping because of my worrying. If I go out and walk, my legs gets very sore and tired much quicker than they ever did before. Additionally, I have been having a very dry mouth and tight feeling throat. My PCP believes it to be either post-viral syndrome, mild MBS, or the least likely, MS. Others have suggested b12 or vitamin d deficiency. I have an MRI scheduled next week and an appointment with a different neurologist.
Other info:
-Was prescribed zoloft and am less than one week in to taking it. I believe it may be increasing the shakiness of my hands and my stress, as it takes some time to adjust to it.
-Was prescribed ambien to sleep. I'll sleep for about four hours straight, but then have a hard time continuing to sleep once I wake up. I believe I might be twitching or jerking in my sleep which wakes me.
-I tried to go to the gym on the 24th and run and lift weights. The next day, it felt like it really set me back, as I was much more sore and my legs seemed more unsteady.
-Began taking b12, b complex, magnesium, D vitamins.
-Had multiple blood tests. The only abnormal result was a positive ANA for speckled at 1:80. I read this can be a pretty common result.
-Less than 2 years ago, I had shingles.
Any thoughts on what could be wrong with me?
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I'm a 20 year old male, overweight and currently/recently fighting a tooth infection due to an abscessed tooth that had a bad root canal. I recently got the tooth removed and I am now on an antibiotic. 7 day cycle amoxicillin 500 MG.
So for the past three weeks I've been feeling pretty terrible. I'll be very fatigued to the point where I don't want to talk or move my arms, I've been short of breath while seemingly doing nothing, I've had heart palpitations with little to no anxiety. My blood sugar feels like it has been low and my mouth is very very dry. Along with the dry mouth I've had difficulty swallowing and a thick white coating with somewhat large red bumps in the back of my tongue. The front of my tongue also seems to have a white coating but it is much thinner. My muscles have been twitching all over but not non-stop. Some days I'll go almost without it. My muscles are achy and when I workout or play sports they get incredibly tired quickly, and are sore for days. I've also been coughing up small tonsil stones. Any help would be appreciated. I'm on an antibiotic but I do want to stress that I've been feeling this way just before I started the antibiotic.
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I have been taking 10 mgs of amlodipine for approx 6 months I have recently stopped due to the following side effects muscular weakness and aching limbs and weight gain I have switched to Hawthorn berry capsules to lower my blood pressure which are available at the herbalist with no known side effects I will record my progress in a couple of months but I am convinced that the doctors of today all too readily prescribe potentially harmful drugs and quite frankly they are more interested in there big cars and enormous salaries than in the health of their patients
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Hi my name is Michele and i am wondering if there is anyone out there who has suffered as much as my grandmother...she has been in really bad shape here is what happened..My grandma was prescribed omeprazole back in July of 2008 for acid reflux...She seemed to be doing fine until the first part of december when she was getting muscle spasms so bad she could hardly walk and is still dealing with the muscle pain, pain in the middle of her chest and her right shoulder so bad that she has to stop what she is doing to catch her breath, this chest pain also came with a rash that was very itchy and dry between the breasts, she couldn't figure out what to do until it dawned on her that it must be these pills...she stopped taking them the beginning of december and is slowly getting better but is getting frustrated with the pain that she is still enduring...is there anyone who has hope for her who has taken this medication who had the same symptoms as her..we do not know what to do to make it easier!!
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I know that it's known that lipitor has the side-effect of muscle tiredness and aches. Has anyone else have to deal with this? Man it's off the hook. I almost am paralyzed fro, lipitor. This horrible and I would like to talk to someone who's been through it. This is a very under-rated affliction IMO. I've been tested and it doesn't look like I have the Rabadolosis<sp? That spelling isn't even close. I was very scared before I realized what was causing this severe problem.. Now I know that lipitor has helped a lot of people, it brought my cholesterol down a bunch very quickly. Frankly i would rather have high cholesterol. I did have a stroke at the end of November, small, deep in the cerebellum. Hence the lipitor.
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i have been taken ezetrol for a long time now and have complained about muscle pains especially in my legs and as a runner it has restricted the amount of exercise i can do. I have had blood test and the enzymes seem to be ok. I have stopped taking them and the symptoms get better and i can run for longer but have restarted taking them. Also i have been told and am in the process of trying it out that the most effective amount to take is the first 10-20 mg after that the reduction is very limited and is not worth taking any higher dose. I was on 40mg and level was 4.6 am now on 20mg and level is 4.9 but the side effects have got slightly better. Overall i feel that these drugs have had a detrimental effect on my fitness
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Although I try to be as active as possible my muscles are making life for me difficult, as for years they have been wasting, causing pain and tiredness. All other symptoms point to Fibromyalgia, which I believe doesn't cause muscle wasting.....also have Osteoarthritis. My muscle problems started in my mid. 30s.....am now 63 and is much worse. Recent blood tests show normal muscles values....but something must be wrong as my energy level is very low. Has anyone been /going through the same??
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for the past week I had severe joint pain and weakness, muscle weakness, bone pain in extremities ( had a blood test for lupus and RA[ no family history of either] Starting to get a bit better as long as I rest. recently sexually active with one person, now I just noticed feeling swollen like I was getting a UTI ( hurt when I urinate), but noticed it hurt in my vagina not urethra, checked and there are 4 small red bumps in my right labia minora and 1 in my left labia minora-odorless, feels inflamed and hurts now. Is this related to possible lupus or separate problem? I feel exhausted and run down.
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for a few days candesartan was helpful then the side effects set in. especially dizziness and arm muscle pain and elbow joint anyone else have this problem
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I've been having muscle weakness and burning in my arms and legs and back for about 8 months now and am so afraid that I have als or ms. I was wondering how long does it take for als and ms to manifest ? This is causing me great stress and depression.
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The last 2 months I've had tightness in my left buttock while on Prednisone. For the first while I could walk if off but for the last month it is constantly there but only when I walk, and sometimes shifts to the left leg's inner thigh, the result being I find I'm sort of limping. Has anyone had something like this? It could be a disc in the lower back pressing on a nerve affecting the muscles in the buttock and thigh, or maybe it's just muscle weakness resulting from the Prednisone. I'm in a quandary how to tackle it, see a physio, chiro, massage therapist. I've found that since I've had PMR 2 years ago anyone working with their hands on me greatly aggravates things so I'm unsure where to turn.
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Doctors found a clot in my carotid artery. This caused a few minor stokes, presumably 5 they tell me, called TIA's. These strokes caused 1 gran mal seizure and another seizure where I was doing the funky chicken for 1 1/2 hours, very scary. They gave me an immediate carotid endarterectomy, scraping the plaque out of my artery, 3 to 7% chance I may have died!! Mending well, but I still have pre- seizure spasms? I'm on 225mg of lamotrigine twice a day. The strokes and seizures caused numbness and pain in my left hip, taking oxycodone for pain. Doc also giving me 5mg zopiclone to mellow me,taken around noon every day, also take 5mg at night along with 30mg of mirtazapine for sleep Does anyone know the interactions if I have a few beer. If anyone has tried alcohol taking theses meds, what was their reaction.
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I am a 29 year old female and I was diagnosed with Hashimoto's Thyroiditis at the start of the year. I have been having problems with my right eyelid in that over the course of the day it progressively becomes droopy and the only thing that relieves it is when I close it. When it becomes droopy it makes my eye feel like there's something in it and I end up rubbing it. It's only when I look in the mirror that it's droopy.
In January my endocrinologist ran an autoimmune profile (but not for every single antibody) and rheumatoid factor and these are the results of it:
Rheumatoid Factor - 9IU/mL (<20 negative)
HEP2 - Positive
Type - Speckled
Anti-DSDNA - 7IU/mL (<30 negative)
(Positive antinuclear antibodies but no significant disease association found)
ENA screen - Negative
Autoimmune profile
Antinuclear Abs - Positive
Anti-Smooth muscle Abs - Negative
Anti-Parietal Abs - Negative
Anti-Mitochondrial Abs - Negative
Anti-LKM Abs - Negative
Anti-Thyroid Peroxidase Abs (Anti-TPO) - 141 kIU/L (<34 negative)
I am posting here because I have a suspicion that I have Myasthenia Gravis. Not only have I got the problem with my eyelid but I tried to follow some physical tests for muscle weakness such as holding my arms out straight in front of me and deep knee bends.The results of these home tests I did:
Holding out arms stretched in front for 60 seconds - pain in both arms when it came up to the 60 seconds and left arm dropped slightly
10 deep knee bends - did all 10 knee bends but the last 3 made my legs feel weak and shaky
5 sit-ups (sitting from lying down) - could only manage 4 sit-ups
I have an appointment with my GP on Friday and since this has now appeared I'd like to mention my concerns to them.
My main concerns are :
Wouldn't my endocrinologist have tested me for Myasthenia Gravis if it's an autoimmune condition? If so what antibodies would she have tested and would any of the ones I had tested have shown I have Myasthenia Gravis?
Who do I need to request to see to get a confirmed diagnosis?
If it is indeed Myasthenia Gravis would it be because my current autoimmune condition made it worse? I have read that this is possible and I became very hypothyroid yesterday as I had very bad Reynaud's flares when out and about.
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I was diagnosed about 4 months ago with Hashimoto's. I'm on 75 mcg of Unithroid. I've started having extreme joint pain and my hands are always swollen. Some days it's a chore to walk up the stairs at work. The only time I feel really good is in the evening about 7pm. Any suggestions on what this could be? Who do I see for my joints to rule out other autoimmune disorders?
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Help! In 2001 I had a thyroidectomy. Immediately, my blood pressure, (which had always been remarkably low), shot through the ceiling and I've been on BP meds ever since. But I digress...
I was always super active. I skied, ran, kite boarded, hiked, biked... all a healthy and important part of my life. I even had booked a trip to climb Kilimanjaro for my 60th birthday in 2010 when I came down with Swine Flu, followed by a couple bouts of pneumonia. When I recovered, I tried to go back to skiing about three months later and found that I had lost muscle strength! I couldn't make turns (and that's a bad thing...) I got weaker and weaker. My doc had no clue. We checked heart, lungs. I was at low end of thyroid and adrenal levels, but "not a problem", I'm told. I'm not a drama person at all, but I really began to believe I was dying because I was getting weaker and felt like my energy was draining away.
At wit's end, I went (for the first time) to a brilliant naturopath who drastically improved my already good died and put my on Chinese meds. It took about three months, but I eventually stopped getting weaker and became stable. That was HUGE! Since, however, I've remained pretty stable and we keep trying other things but nothing has put me even close to where I was.
The best guess is that its related to thyroid or adrenal function. I dunno...
I can now make between 6-10 stairs before I have to stop for a few seconds to regroup. I can swim very short distances but never alone because when I run out of energy, its GONE and I have absolutely nothing left. This has drastically impacted my life and I want to be strong again!
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