Olanzapine :: Bad Feelings While Quitting
Jan 4, 2016
I recieved super bad feelings when i got under 100% dose of olanzapine and couldn't sleep and up-ed my dose to 10mg (from around 6mg i guess). the feelings came when i was falling asleep.
it came like 3 times, like 70% of my cells were being pressured together.... (i'm describing the super bad feelings) it scared me A LOT when it happened and i am very scared to up my dose again because i think then these super bad feelings might come again...
they came for like 7 seconds these 3 times combined, these 3 times happened in like 1 minute. it would not surprise me if these super bad feelings were Life-threatening but i told my psychiatrist about it and he didn't know what it was but said that it was not Life-threatening.
so now i am trying to quit very slowly so i never have to up my dose again. lowering my dose by 0,625 mg each time.
i was hoping that someone here knows what these super bad feelings were and could shed some light on it. it would help me ALOT if i knew that these super bad feelings were not dangerous.
i'm not 100% certain that these feelings were caused by me uping my Olanzapine dose alot but i think so.
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I'm guessing you've tried the usual suspects, zopiclone, temazepam etc etc
When my insomnia got so bad I couldn't even function any more, my psychiatrist tried me on a low dose of olanzapine. It did help me. It is also a pig to get off though... There are no easy solutions I'm afraid. CBT did help me too, but I had to really work at it.
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Does anyone have personal experience of this problem? A 79-year-old friend with vascular dementia has been prescribed a whole series of atypical antipsychotic drugs over the past eight months, all with varying disastrous results. And yes - I know this is an off-label use of this group but they still get prescribed for dementia sufferers all over the western world.
She's been on mirtazapine 20mg once daily for about five years (with no apparent ill effects) and olanzapine 10 mg once a day for three months. Two months ago she very rapidly - over a few days - developed massive swelling of her left hand, with complete loss of use of the middle, ring and little fingers of that hand. An X-ray was inconclusive, mainly as she couldn't straighten the three affected fingers, and her doctor has been mystified by this ever since. He finally decided it was arthritis but it didn't look much like it to me, given the degree of swelling and deformity, and the speed with which it had come on. Anti-inflammatory drugs have been prescribed, but with minimal effect.
I visit her in her high-security psycho-geriatric unit at least three times a week. Last Tuesday (six days ago) she was still feeding herself perfectly normally with her right hand, once her food had been cut up for her. Three days later, she could no longer hold a spoon, fork or cup. Her right hand isn't swollen but I can clearly see the identical deformity in her last three fingers as in her left hand. All three fingers on both hands are curled up and twisted over each other.
After raising Cain at the home, I've managed to get her an emergency appointment at a rheumatology clinic tomorrow. In preparation for this, I've been doing some research over the weekend (and no, not on Wikipedia) and have discovered peripheral oedema (swelling) is a rare, but known, side-effect of olanzapine. I also found a long paper that had clearly been published in a learned journal on the subject of peripheral oedema with combined mirtazapine and olanzapine use. Unfortunately, it was in Turkish!
Has anyone suffered from this and how quickly did it improve once the olanzapine dosage was reduced? Also, how serious is the rebound psychosis when olanzapine is withdrawn?
She was originally on risperidone, but when that had to be tailed off because it left her with severe Parkinson-like symptoms, it left her way more psychotic than she'd been at the outset, with the result she stabbed another resident in the lovely retirement home she was living in. She's stayed that way ever since, hence the transfer to a grim high-security psychiatric unit, where she'll end her days. She was subsequently put on clozapine for a couple of months, which caused terrible athetotic movements - constant bobbing, weaving movements of head, jaw, tongue, arms and upper trunk - which made her life unbearable. I have to say, however, that when that was gradually withdrawn, I didn't notice any rebound psychosis.
I'm furious with myself for not researching this sooner, as I'm a former nurse, though neuro was my speciality. I'm even more furious with her idiot doctor for prescribing a med that isn't authorised for dementia, then failing to notice she was suffering from a known side-effect. Ditto the nursing staff at the home. When I mentioned this to the head nurse today, she blithely said she'd known all along it was a side-effect of olanzapine - though I suspect she was just covering up her ignorance.
My friend is beside herself, and it breaks my heart to see her like this. She knows there's something wrong, but doesn't understand what it is. She can't feed herself at all now. I tried her with a biscuit this afternoon and she couldn't even hold that. She's already dangerously underweight (BMI 17) and now she's refusing to let the staff feed her, as she's not used to that. I'm the only one who's allowed to feed her, albeit only a few mouthfuls, but I'm 71 myself and can't continue going in twice a day. In the meantime she's screaming and shouting all day and all night in anguish and sheer terror, and attacking everyone who goes near her. She tried to bite my face today.
Sometimes patients who've been on this class of drugs for long periods know much more about them than the professionals, which is why I'm posting here. Is this terrible condition likely to be a result of olanzapine (and possibly mirtazapine)? And can we expect severe rebound psychosis if her doctor tails it off? (Always assuming he even agrees to do that.) Also, does anyone have any experience of other recently-developed anti-psychotics that don't cause appalling side-effects of one kind or another? Though I have to say, from my own nursing experience, that I suspect there's no such animal.
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I had a similar problem eight years ago, a few months after a heart attack and 9/11. I was absolutely terrified of everything. I couldn't even go near a McDonald for fear of them being a terrorist target (no great loss there then!!).
Then as now I would start crying at the drop of a hat - though this time I have managed to hide it from the family. At work I find myself in a layby,head in hands and sobbing like a baby and wondering if it's all worth it.
I don't really feel suicidal - I'm too scared to try anything in case it goes wrong and I end up a cabbage !!. My wife is an absolute gem in these times as she is under a similar pressure to me but copes with it far better than me. Perhaps it's the 'man the provider' scenario that affects me as I feel I should be able to provide for my family better than I do. The wife had a few weeks 'between jobs' but had agency work here and there so we got a bit behind with things like the rent and HP payments on the car etc. I do all the overtime that I legally can (being an HGV driver means you can only work so many hours by law). She has a permanent full time job again now thankfully so I know things will slowly improve over time but I still can't get rid of the feeling that I have let the family down and that we wouldn't have been put in this situation if I had done something - but what?.
As you can tell my problems are 90% financial. Theory says that now we have more money coming in again that things will improve. That's what I keep telling myself anyway. Even though I am signed off I am still worrying about work - is somebody doing my work properly - are they looking after my truck? etc.
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Now, you've probably clicked on this link and have some serious doubts about what I'm going to say.
Quitting smoking is the easiest thing you can do and why? Because you don't want to do it in the first place.
Example 1: Let's say I invite you to your favorite food, would you say yes?
Of course you would, it's something you enjoy and it's free.
Example 2: What if I invite you to eat dog poo. Would you try it? Hey, it's free, right! But, you would probably say no.
So what do those 2 examples have in common? The #One you want to do and the other one, not so much.
Well, let's pretend I chase around the house, work and every area of your life, telling you to eat dog poo. Would you just give up and try it? Like really?
Because that's what addiction does it pokes you and chases you until you agree to do it.
I could write a whole essay on this, but I'll post some main ideas first and then will specify on some things.
Addiction is not a habit. Look it up in the dictionary. Not the same thing at all and the words are very different, even though they sound similar.
Psychiatrists classify addictions as a mental disorder.
So first admit and you've probably noticed that by being a smoker, you are different than other people. You think differently and you're aware that your life is dominated by cigarettes. When to buy, smoke etc.
If you smoke a pack a day, that's like 1 cigarette every 45 minutes, without counting 8 hrs of sleep. That is like brushing your teeth the same number of times a day. Doesn't sound like normal behavior right?
So, let's summarize this, smoking is an addiction that pokes you several times a day. And here comes the catch, why do you have to do it, just as the example with dog poo.
Because you think you are getting something out of it. Not the bad consequences, but you think it somehow lets you decrease your stress or keep emotions in control... etc..
There are two types of addictions, physical and mental. The mental part of the addiction is usually what makes it seem impossible to quit.
But there's an easy way.
Add your thoughts in some things I've said or ask more questions and I'll write some other posts that go deeper on why smoking becomes a problem and it's our mentality that makes us fail.
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I'm currently in prison, been taking methadone for about 6months 2 or 3 a day no more than 30 ml but I decided to quit because not the best thing to do in prison, ( I'm not even prescribed to it) it's been 3 days since I took my last one and honestly I'm not having any major WD , yeah of course I feel weak and uncomfortable but I still manage to eat and sleep so far, I just been reading other's post and most of em saying methadone WD takes weeks even months to feel normal, I don't wanna be stack in my cell for weeks and not be able to protect myself if needed, anybody knows how long does methadone WD takes.
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