Lupus :: Positive ANA And Positive Anti-dsdna
Jul 24, 2013
So I have been sick with a mystery illness for the last year or so. I've seen every specialist, and the first thing they looked for was a malignancy, but there seems to be nothing. Then I saw a rheumatologist and she sent me for blood tests that came back with a positive ANA and positive anti ds-dna. From what I've read, positive anti-dsdna is VERY specific to Lupus. I never thought I had Lupus because my symptoms weren't specific to it, but after ruling almost everything else out, I'm thinking more and more that Lupus could be it. Because my symptoms weren't specific enough, my rheumatologist told me she wanted to see me again in 3 months to see if there were any progressions. I'm really becoming more certain that it has to be Lupus with these positive tests, and I'm worried that I won't be able to get a diagnosis for a long time to come.
Some of my symptoms include:
Extreme fatigue
Constant low grade fever
Neck discomfort
Headaches
Random pains in fingers and knees (not constant, every once in a while)
Chest pain when breathing deeply
A lot of memory problems
Thinning hair
Can barely work out or walk at the same speed as most people
What do you think I should do next in order to speed up finding a diagnosis? How do I make it clear to my rheumatologist that I feel like this is becoming more and more urgent?
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2 years ago it was ANA 1:80 and the anti-dsDNA was 10, now it's ANA 1:40 with anti-dsDNA 22. So which is worse ?
2 years ago they said it's borderline and if I don't have symptoms, let's wait, they didn't dx. me with lupus.
I had ( and still have ) unexplained hip pain ( comes and goes ), headaches and lightheadedness ( had them before, but usually around periods ), but 2 months ago they become very bothersome and almost constant. My vitamin D is 25 ( should be 30-70 ) and vitamin b12 is 244 ( should be 200-900 ) my dr.said is still kind a low
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Are these lupus symptoms at all ?
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The short version of my story is I went to a fertility doctor after having trouble conceiving my 2nd child and having a miscarriage..the dr ran a ton of blood work and I came up with with a positive abnormal ANA (no numbers listed) and a positive high anti dsdna at 38..I think it said over 9 was considered positive. I have zero symptoms of lupus and am now scared to death I have lupus. Could this mean anything else??I have an appointment with a rheumatologist next week but this is the hardest week while I wait. I spoke to a friend's aunt who is a rheumatologist and she thinks the positive anti dna is rare in people in my age to be false (i'm 32) and thinks I may be developing lupus. I am assuming the rheumatologist will re-run all these blood tests and add some of their own but could this be something else? or nothing at all?
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Are these anti-bodies found in people that do not have lupus? I have both, but the numbers are very low, so they're not flagged. I've seen in a number of places online that anti-dsDNA and anti-sm are pretty exclusive to Lupus.
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I was diagnosed with fibromyalgia years ago due to constant and sometimes debilitating muscle and joint pain. I am seeing a new PCP and she ordered some blood tests. The first was just a general screening but my c-reactive protein came back as elevated (also my platelets) so the doc ordered an ANA with reflex if positive. ANA came back positive (no titer information - it was just a positive/negative test I guess) and anti-SSA came back at 8.0 (negative range is 0.0 to 0.9). But RA factor, anti-centromere B antibodies, anti-dna (ds) qn, anti-jo-1, anti chromatin, anti scleroderma-70, rnp, anti-SSB, and smith antibodies are all normal.
Besides my muscle and joint pain I have had periods of alopecia (losing quarter to half-dollar sized patches of hair on my head), full-body rashes during especially hot times, asthma, and suspected endometriosis (currently controlled by depo-provera). I also used to never get sunburnt but my face especially gets really red now if I am in the sun for more than a little while. I have darker skin so its sometimes hard to see but lately my cheeks and nose seem constantly flushed.
All of these symptoms have been spaced out and gradual so I never thought anything of each individual symptom. The alcopecia was blamed on "stress" when I went to the doctor for it. The rashes I blamed on a simple "heat rash". My pain was diagnosed at first as carpal tunnel and then as fibromyalgia. But now with the ANA and anti-SSA tests I am thinking it all may be related. But I don't know and my doctor is out of town, and although I know she will refer me to a rheumatologist now as we have talked about that, who knows when I will actually be able to see the rheumatologist. So any thoughts would be greatly appreciated. I am thinking maybe SLE (lupus) but with only that one anti-SSA and none of the others I don't know. Also I do have flares 2-3 times a month where my pain gets much worse but it constantly hurts and aches the rest of the time regardless, which doesn't seem like typical lupus. Oh and I also had severe fatigue until my doc put me on Savella which helped with the fatigue but not the pain. So now I am on gabapentin also but it doesn't seem to help too much either.
I would do almost anything just to be pain-free for even just a day. I am hoping with the ANA results now the doctors will not only maybe be better able to treat me but also will take my pain seriously.
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My new girlfriend, who I like very much, was very open with me about the fact that she had a blood transfusion as a baby for several surgeries she had to have, which left her HCV positive. She and I were about to move into the sexual part of our relationship, so we both got tested for STDs to show each other we had a clean bill of health. Well as it turns out, her bloodwork showed she was HCV positive again...this is after achieving SVR (not sure for how long she had achieved this yet). She told me and was very upset, so I obviously just gave her a hug and held her. No other way to respond she was so upset. I'm curious, does anyone on here have any experience with this? Possibility for false positives or possibility for her to need to seek additional treatment? I hope you can forgive any questions that may seem ignorant. I am mostly focused on her health, but naturally I'm also concerned about the implications for our future relationship (I understand it is very low risk to pass it to me through sex, but still, I'm human, and I'm just carefully looking at this situation). If anyone can shed some light on her situation, I'd love to hear it. She's a great woman and I'd like to get any info for her that could help.
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I went to the urologist and did a swab and urine test. The test came back positive for Chlamydia. I was shocked because I have been with my girlfriend for 8 months and we lived and worked together for about 3 months now. We are literally with each other 24/7, so I know she didn't give it to me. Also, she got her full gyno screening about a month ago and everything came back negative. Since I didn't believe this test, I went to a third doctor and took a urine test. I came back positive for 2 things now -- Chlamydia and Gardnerella. How is it that I took this test 3 times and got 3 different results?
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