Liver :: Cirrhosis, Elevated Creatinine And Sovaldi
May 29, 2015
I just need to ask that my father was on sovaldi treatment for 4 days when his (serum) creatinine level shot up to 2.53 which later came down to 1.96 and now at 1.43. He has no renal impairment and his kidney ultrasound and detailed urine report is perfectly normal. He is cirrhotic (Hep-c) at stage 2 according to doc (hep-c) which stopped the sovaldi + ribavirin treatment to save his kidneys. However during the period he was also on diuretics (furosemide) occasionally. His nephrologist says that it is safe to continue sovaldi treatment but the other doc gave a red flag (I have yet to have a discussion with the nephrologist). So I am asking that is it possible that creatinine levels change because of sovaldi or do i need to the change my doc? Also he has edema occasionally. He also has acid reflux.
Age: 58 Sex: M Height: 5'10" Duration: a year (stopped sovaldi: a month) Location: Pakistan Medical Issues: Hep-C, 2nd Stage cirrhosis, acid reflux, depression, anemia Medications: Furosemide (Depending on edema) Rabeprazole (Twice daily half and hour before food) Folic Acid Vitamin-D and Calcium
View 1 Replies
Advertisement
Has anyone experienced low BUN and creatinine blood test? How is it common in people who have cirrhosis?
View 5 Replies
Been feeling lightheaded and brain foggy and a bit sick recently with some stomach grumbling and pain. Went to the doctors who did repeat blood tests over the course of 8 weeks and have said my enzymes are slightly up which could be the result of mild fatty liver. My question is does this sound related? He's also just tested me for celiac, but told me in the beginning that I could be fighting a virus. I'm worried that the 3 diagnoses he's given are so different I don't know what to believe, also does this mean I should be less worried about the tests because they are low enough to be anything?
View 2 Replies
I was urinating very frequently, usually small amounts. Did a home urine dip test and found white and red blood cells (no nitrate) so went to Dr. who took blood. Blood results = slightly raised creatinine, urea and potassium. What could this mean?
View 2 Replies
I had some blood work done last week any my Creatinine was 1.15 and my GFR was 57. I know these aren't alarming numbers necessarily, but 6 months ago my Cr was .72 and my GFR was 100 so it's a huge change. Everything else (BUN, BUN/CR ratio) were normal. Doctor was unconcerned and wanted to check in 3 months. Anybody have any thoughts on this? I do take lots of supplements but have taken them for years with normal kidney function. Also have taken a lot of Benadryl lately. I'm stumped at this big change. Also I am not diabetic and do not have high blood pressure.
View 1 Replies
my dad is in hospital at the moment. he has liver cirrhosis and he's in a bad way. i'm trying to find out whether he has a chance of getting back to his old self. he has jaundice his arms have gone really thin. he has had GI tract bleed. a stomach ulcer, swollen stomach and his toxics from his waste are going to his brain. when i've seen him he is just confused or sleeping with his eyes rolled back in his head. any ideas on whether his body could recover for a while or whether this is game over.
View 2 Replies
I am a 34 year old male who was diagnosed with hemochromatosis only after a liver biopsy because i only have one of the genetic markers. When diagnosed my ferritin was over 5000. Shortly after i was diagnosed with stage 4 cirrhosis of the liver. Is anyone out there in the same boat as me.
View 14 Replies
I have high blood pressure and I have renal panel test done every 4-5 months. This is my 4 time and my results came back with increased creatinine 1.68 ( maximum range 1.4) and my gfr was 48. Bun was within range.
Last time when I performed the test 4 months backs the creatinine value was 0.96.
My doctor switched me from tribenzor to axor as my bp reading were normal around 110/70. I test my bp at home weekly and they never cross 120/80.
Can I get my creatinine and egfr values improved or am I professing fast on ckd.
View 2 Replies
What is the sensitivity of liver nuclear scan in detecting cirrhosis?
View 1 Replies
I haven't been in here for awhile, My husband took harvoni and is free of hep c, He has been on the transplant list for 4 years, He had the tips procedure done in 2011 because of a bleed out that almost killed him, He has had liver cancer, They probed the cancer and it is gone, He is on lactulose because of H E , Also he vomits every third day and no one knows why, So we had a meeting with the transplant doctor yesterday, and because his hep c is gone and his meld score is only 16, They took him off the list, I asked what would happen if he got worse or whatever, And they said we would have to start over again, So now we have decided, no matter what we have been sitting too long , it's time to enjoy life and start traveling, Whatever happens ,, happens,,, Had to vent Thanks
View 1 Replies
I have been diagnosed chronic hepB for 8 years now my spleen is inflamed.
View 4 Replies
A C/T of the thorax, done because of shortness of breath, showed the right diaphragm and liver situated in the chest cavity. Other tests of the thorax and abdomen, including a PET SCAN, have not shown any reason for this.
What can be the reason for the elevation of the diaphragm and liver?
View 1 Replies
One of my friend has Lupus Erythematosus and needs a liver transplant, but during the blood transfusion, she got HCV. She wants to take daclatasvir or sovaldi(sofosbuvir) for curing HCV, but is worried that daclatasvir or sovaldi(sofosbuvir) would have side effect that is bad for Lupus Erythematosus. So I wonder if Lupus Erythematosus patients take daclatasvir or Sovaldi(sofosbuvir) for curing HCV? Were there any successful or failure previous examples?
View 1 Replies
I had gastric bypass and was found to have a fatty liver and enlarged spleen elevated white blood cell count and pain when I take a deep breath..should I be super worried?
View 2 Replies
Are these two tests the same thing? Also, we are having trouble reading my mother's blood tests - and yes we have an upcoming appt but the office is very busy. She has a Protein/Creatinine ratio of 4.75. Her U creatinine is 60 and her protein is something like 13.
There isn't a normal range for the Protein/Creatinine ratio, though I know in the past it's been something like 0.83. Her blood creatinine was steady for her ... 1.9 and her GFR steady for her at 28. So...I don't get how the protein can be so much higher than it was before.
Every time I look up protein/creatinine ratio - I keep getting "albumin" results. Is this the same test?
View 1 Replies
My mother is a 65 year old female, 136 lbs, and on peritoneal dialysis for 3 years due to End Stage Renal Disease. Last week, she began experiencing severe abdominal pain that was a burning/gnawing pain. She went to the hospital and a CT Abdomen was taken without contrast. All was normal.
Over the next four (4) days, the pain persisted, particularly during dialysis exchanges at home. She returned to the hospital who admitted her. Another CT Abdomen was taken at this time which showed "nodular contour on the liver", free air in transverse colon which appeared to be dilated. She was also constipated for several days during this period. The CT impression suggested clinical evaluation for chronic liver disease.
A standard liver panel was taken and all results were normal. Nothing even close to elevated. She has never had a history of any liver issues and never had anything show on a CT for liver. After a day in the hospital, all stomach pain disappeared, she was able to use the restroom, and all stool samples/GI tests were normal without blood. She is naturally anemic due to ESRD with low iron/protein. Her last ANA/autoimmune panel was in December, all clear. No history of any hepatitis.
An Ultrasound Right Upper Quadrant was performed and the impression was no biliary obstruction, moderate ascites (tends to be normal due to peritoneal dialysis fluid), and "heterogeneous liver." The impression suggested referral for cirrhosis evaluation.
She began taking Hydralazine (25mg/3 times daily) in the last 3-4 months. She also takes a host of other blood pressure medicines.
QUESTION: She is currently awaiting a kidney transplant and very worried about this. A blood test will be taken in a couple weeks by a specialist that is supposed to diagnose Cirrhosis. Given this presentation alone, what other causes could explain this imaging results? Should we fear the worst?
View 3 Replies
I had an abdominal ultrasound done for some abdominal pain and it was noted in the report as an impression that I had an echogenic appearing liver (such as non alcoholic fatty liver). My doctor at that time didn't tell me and just said my report was normal. When I went in for my Colonoscopy that was unrelated, it was mentioned again and when I did some research I realized what fatty liver actually was. I switched doctors.
My new doctor is considering giving me a CT scan but is checking with the GI department to see if they think its needed, etc. etc. But that there is no treatment for it besides diet modification.
Here's the thing. I don't have any of the risk factors. I am not overweight. I'm actually underweight slightly (BMI is 18, I weigh 110 lbs). I don't drink any alcohol, never did. And I don't have diabetes or hepatitis. The only thing I could do and what I have been doing is change my diet. I stopped eating processed foods, watched my sugar/carbs, and eat more vegetables than I ever have.
I'm a very anxious person and I'm not sure I want to know what the scan says. If it's worse than what I thought, I'm going to be so upset and stressed out. And I can't treat it anyway. It's not like they can give me a medication and make it go away. I think knowing the extent of it will just cause me mental anguish and I'm already stressed out about it as is.
View 1 Replies
My Cholesterol was 7.8 and I was put on Statins 3 years ago. Because they gave me pains in my legs and other areas I stopped them.
A year ago my Cholesterol was still high and I had changed doctors and was prescribed Atorvastatin 10 mg after 2 months my doctor sent me for blood tests and in a phone call when I was at work he told me that Atorvastatin had caused Liver damage. He said I should stop taking the tablets immediately, pity this advice was not put on my notes so that when I phoned for my blood results a week earlier the receptionist could inform me to stop Atorvastatin. She just said Doctor will be in touch via phone call next week
He referred me to a Liver Specialist.
I went to see Liver Specialist after having Liver Ultrasound. Fatty liver was diagnosed and Liver Specialist promptly put me back on Atorvastatin claiming this would help my fatty liver. I couldn't believe it but what could I do?
Local GP had advised me to have bloods done again after being on tablets for 2 months. When my results came back the Locum doctor I saw said "whoa your Liver is not happy" STOP the tablets and have a blood test in 2 weeks.
2 weeks later Liver levels are coming down so thats a good direction. Dilemma is I have to see my Liver Consultant 16 June 2015. Wish me luck!
View 9 Replies
this isn't about me but is about my girlfriend who is about to have gastric sleeve surgery.
She is a 40 year old women that has had a full hysterectomy and has type 2 diabetes. she has had a history of thyroid and weight issues. she is 5,7 weighs 225 LBS. she has an enlarged fatty liver of 27cm and the Doctor said that she needs "emergent" gastric sleeve surgery to bring down her enlarged liver. this was claimed on this past thursday. I have been looking high and low for documentation and statistics on using the surgery for reducing fatty livers but can't find any information. Does this sound right? has there been a history of using this procedure for such cases, I'm worried and scared for her.
View 1 Replies
I've recently had 2 LFT that both showed raised enzymes, I've had a scan and it shows I have gallstones, however I am currently undergoing investigation into whether I have Reactive Hypoglycaemia, my question is that if I do have RH, would this cause my liver enzymes to elevate?
View 2 Replies
IiIt was picked up by chance thaI have fatty liver, could have had this for years without knowing about it, how do I find out how much damage has been done already if any? My GP does not seem too concerned about it, all my LFT have come back normal so what can I do about it apart from lifestyle change which I'm doing already?
View 13 Replies
