Herpes :: HSV2 Symptoms But Blood Test Negative


May 30, 2014

I'm pretty sure I have HSV 2 (herpes) but I never got a culture, never had noticeable recurrent outbreaks, and have had a negative IgG blood test so I'm a little confused and want to know others opinions.

Almost exactly 2 weeks after unprotected intercourse I got:-

-3 hard red bumps/sores in a row in my pubic hair region (about the size of a pencil eraser)

-A few days later: extremely itchy vaginal area and thick, yellowish smelly discharge which lasted a couple days

-Possible "flat" sores on labia minora area (white circular discoloration, did NOT look like typical herpes sore clusters)

-The red sores on my pubic area seemed to crust over/come off (became flat, smooth, and whitish) after about a week then went away. I never noticed any fluid in them or oozing.

I never experienced any swollen lymph nodes, flu-like symptoms, or clusters of white pimple-like sores. I have never noticed any re-current outbreaks. I have no history of HSV 1.

Two years after possible initial outbreak I finally got a blood test: HSV 1 & 2-Specific Ab, IgG; Venipuncture

HSV 1 IgG: <0.91 Negative
HSV 2 IgG: <0.91 Negative

(index: 0.00-0.90, Equivocal .91-1.09)

I know there are lots of cases of people not producing antibodies, so I'm wondering if it's worth getting a Western Blot? Do you think the only explanation for my symptoms is herpes?

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I had an encounter with a CSW Feb 2015 that involved unprotected oral (stupid I know) but protect vaginal sex. The next day I had a strong itch on my groin and the following day (2 days after encounter) I had a blister cluster of about 6-8 blisters in that area. The blisters went away without any scabbing within 1 or 2 days and never reappeared. I have had a almost near constant itch/tingling in my crotch in the same area ever since.

I had assumed this was a HSV-1/2 outbreak from what I had read, and I was unable to visit a clinic at the time. 13 months later, I get the IgG test and my results are:

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Herpes :: HSV2 Outbreak Itching And Blisters On Wrist And Leg

I was diagnosed with HSV2 about a month ago, during which I had my first classic outbreak. I got it from my boyfriend, who did not know he had it at the time. I was tested negative for HIV, hepatitis, and syphilis at the time I was diagnosed. During my primary outbreak, I must have somehow touched the sores or the fluid and in the same week one large blister appeared on both my left wrist and left leg at the same time. I was put on Valtrex for 10 days and the genital region cleared up pretty quickly, but the ones on my wrist and leg took longer and I don't think they ever fully healed because there was always a red spot in those areas.

This past Saturday it came back but only on my wrist and my leg, not in the genital area. It started as just itching then by Sunday there was an appearance of a cluster of blisters in each area, where the first time there was only one in each spot. I went for a follow up appointment to my gynecologist two days later and showed him the blisters. But he was not very helpful; he said he only deals with the genital region and I had to see an infectious disease doctor. He gave me a permanent Valtrex prescription to take daily and I've been on it for 4 days so far and did the swab test on my wrist to confirm it was herpes. I could not get an appointment with the ID doc for another two weeks, and Tuesday night the spot on my leg was huge and red and swollen with cellulitis all over the area. It is on my lower calf close to my ankle, but I'd say the entire surface area that is infected is about the size of my fist. I went to the ER and they tried to tell me it was a staph infection despite hearing my story and put me on an antibiotic without answering any of my herpes related questions. It has been 4 days since I'm on Valtrex again and I've kept the area bandaged at all times and worn pants and long sleeve shirts.

Sorry for all the background, but I thought it would be helpful info to best answer the questions I have. I am concerned that for the rest of my life I'm just going to be a walking contagion that can spread the virus to everyone without knowing it, since HSV2 spreads frequently asymptomatically. I know that Valtrex reduces the number of outbreaks I'm going to have, but I'm more concerned with the areas on the exposed parts of my body and want to know exactly which parts are contagious to others and if I'll be able to tell or I will have to keep both areas covered the rest of my life.

My appointment with the ID doc isn't for another two weeks, and I cannot wait that long to have these questions answered because I'm getting sick over this.

These are my questions (please only answer if you've experienced this yourself or you are an MD, I know it's a unique case):

1. Will the areas on my wrist and leg always be a site for a breakout, and will these areas always have the potential to be shed asymptomatically?

2. What part of the outbreak is actually contagious? Is it anywhere that is red, or is it mainly just the blister itself? Will bandaging only the blistered area during an outbreak protect the virus from spreading to others or can it spread from any part that is red?

3. I've read that once it is in an infected area, the virus can spread to other parts close by on that same area, so is there a potential that the next outbreak will be further spread out on my arm, thus giving my whole arm and leg potential to shed the virus?

4. Will it always break out in those spots? I find it curious that this second outbreak (or continuation of a primary outbreak) only appeared in those spots and not the genital region.

5. I know women with HSV 2 can still have babies, but I'm concerned that if I have it on my wrist that I will never be able to hold a newborn baby. I know obviously if I have visible sores that I should avoid a baby at all costs, but what about when there is nothing there and it sheds without me knowing?

6. I'm concerned about it spreading to other parts of my body. I know auto inoculation is rare after the first outbreak, but my wrist is too close to my face for me to be comfortable.

7. What about shaving my legs? I know when there is an outbreak I should avoid the area completely, but when there is nothing there can I still shave over the area or will that spread the virus to other parts of my leg?

8. Manicures/pedicures used to be a huge part of my life. I would never want to infect anyone with this disease. Would it be safe to tell them to only touch my hands and my toes, or is this too risky?

9. My gyno placed me on a permanent Valtrex prescription. Is there a risk associated with becoming too dependent on antiviral meds, or a chance that the disease will become resistant to the medicine? I've also read that being on permanent antivirals can cause the virus to mutate and cause different strains.

I know this will probably take anyone forever to read, but I had to get this all out because these questions have been running through my mind for days and no doctor I've talked to so far has been able to answer them.

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I'm trying to really believe in those (just under) 6 week duo negative results before I go for my next test, but my anxiety has basically not allowed me to relax or accept those results being at least a strong indicator. I even called the Pennsylvania state hiv hotline a few weeks ago, and they said a 4th gen test at the point when I took it was MORE than ample time for the antigens/antibodies to form to a detectable level, that the 4th gen test is the best test available in the world, and at that by 5.5 - 6 weeks that was more than enough time for the 4th gen test to provide a correct, conclusive result. She basically told me over the phone that my test result was conclusive and my symptoms don't matter.

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(which I am about a week or so away from, whenever I drive up the courage to go in--as much as I want to hear negative and breathe a sigh of relief and just move on, I don't know if I'm ready to hear the results are positive if that's the case).

I've just been engulfed in this stuff all summer, googling constantly and reading and self diagnosing and building anxiety. I was even up the mountains at a bachelor party this summer and found time to sneak away from my friends to Google hiv symptoms and test info---it's become obsessive.

I've read some posts that say a duo lab test which is negative anytime after 4 weeks is conclusive, and that is essentially what the hiv hotline advisor told me as well, some places said 6 weeks, etc, but I just have a hard time accepting that, esp with the cdc guidelines of 3 months, and with the symptoms I mentioned having.

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(Also I am I 29 year old heterosexual white male living in USA, in good shape, workout often, never have done drugs or cigarettes, rarely drink, and I have always had a strong immune system. Also, I am feeling fine physically currently, even with the symptoms I mentioned having now. Anxiety level still high though.)

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I am considering taking another test or perhaps going to get a rapid blood test. I know my odds of being positive are extremely low but I keep focusing on the what if. Please help and thank you!

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