Graves Disease With RAI :: What Happens To The Antibodies (autoimmune ?
Nov 27, 2013
Say you have been treated for Graves Disease with RAI and that deals with the hyperthyroidism (not so much with the eyes though!), what happens to the antibodies that were attacking you thyroid with such vigour and verve? Do they just go home because there's nothing left to attack? Are they always in your system waiting to attack public enemy number 2? And why do these things decide to attack the very thing they are meant to be protecting? Is it genetics? Childhood illness (whooping cough, measles and mumps in my case.) Environmental factors? Stress? Diet?
I am sure there are many schools of thought and theories to all of these questions but I am curious still about where these wee anti-bodies go after the illness (or symptom of your illness) has been irradiated in my case.
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I'm wondering if anyone has any advice regarding diagnosing graves and thyroid eye disease in pregnancy. Having never had any problems until being pregnant I'm very confused as to why I've suddenly got it? At around 12 weeks into my pregnancy I noticed a change in my eyes (one was protruding), after seeing an eye dr, he advised I'd be tested for hyperthyroidism and following his advice the bloods came back as a positive for hyperthyroidism. I was put on PTU by an endocrinologist for the rest of my pregnancy and at week 39 I noticed a yellowing in the White of my eyes and admitted myself to the maternity unit for blood tests following speaking with a midwife. It turned out I had developed severe jaundice (Which I now have learnt through research to be a severe side effect to PTU) and that my liver was failing; I had to have an emergency c section that night. I am pleased to say I have a had a healthy baby boy but I'm so anxious as to whether these conditions will worsen post pregnancy.
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I have just been diagnosed with graves disease (and overactive thyroid as a result) and prescribed 3 5mg carbimazole pills a day whilst i wait to see a specialist and have an ECG so i can also be prescribed beta blockers.
My doctor said to take all 3 pills at once but i have read that the effects don't last 24 hours and its better to spread them through the day. Does anyone else take 15mg and do you take them all at once or spread out? In your experience when is the best time(s) of day to take them?
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I Am wondering if someone can help me out with what my blood results mean . ok so i went to a walk in clinic because i was having a laundry list of stuff going on with my health . asked doc to do some blood work and see if he could find what might be wrong .
blood work came back showing some thyroid issues . my TSH was .16 my T4 free was 18 free T3 was 6.1 and my TPO was 102
the doc said i have Hashimoto's thyroiditis and referred me to endocrinologist which im waiting for appointment .
so my question is after doing some googling im wondering if the doc might have meant to say graves disease rather than hashimoto's . it was very busy in the office and maybe he just mixed the two up ? the reason im thinking this is because when i look at what my blood work results are they point to hyperthyroid rather than hypo . can anybody tell from my numbers i really would like to know and its a bit of a wait till my appointment with the specialist.
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I am very new to this site and extremely grateful that I found it. I was diagnosed with inappropriate sinus tachycardia almost three years ago. I am taking 350 milligrams of metoprolol. My primary doctor ordered new labs since my cardiologist has not requested any in the last 2.5 years. My results are as follows:
TSH - 0.01
Vitamin D - 26
Carbon Dioxide - 18
Free T4 - 1.3
Thyroglobulin Antibodies <1
Thyroid Peroxidase Ab 421
Primary doc originally thought I graves or Hashimoto's, but now wants me to follow up with an endocrinologist. Of course that appointment is 2 months away.
I do not have many symptoms. I do have the feeling of warmth in my shins, but that comes and goes. I have a little muscle weakness. I have been having trouble sleeping through the night, but 2 glasses of wine have been helping.
If I do have either Graves or Hashimoto's is waiting 2 months for a doctor appointment ok? I would think that I need some type of medicine.
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I've been taking carbimazole 20 for 2 months now as i have graves i had a uptake scan which shows its my whole thyroid gland is playing up .up and down so my specialist had gave me carbimazole to block my thyroid hormones and replacing them back with thyroxine 50 i feel so terrible sickley cant eat well also headace i believe the carbimazole is causing all the trouble.with side effects.
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I have posted to this Board before about what has made a difference to my recovery from Graves. In addition to the medication Methimazole, I started on Regular L-Carnitine and then later Acetyl-L-Carnitine and vitamin D supplementation. Others on the Board have posted about the addition of selenium as well as other natural herbs such as Melissa and Bugleweed. I saw this posting on another Hyperthyroid Board and the author has given me permission to copy it to this Board as follows:
I am shocked that our doctor's don't know more about the thyroid, autoimmune disease and its connection to the gut. I went to a naturopath when I was first diagnosed in 2012 because my husband and I didn't like what the endo suggested. After seeing the naturopath we made a connection between my occasional IBS type symptoms, bloating and my thyroid. We started a probiotic and immune support vitamin called Moducare. Then she ran food sensitivity testing through All Tests labs (some MDs are skeptical about this but it worked for my stomach). I had all four antibodies for graves and Hashimoto's and I had symptoms from both and almost undetectable TSH levels. She removed gluten and dairy from my diet and pulled out foods I tested sensitive to like yeast. Then added Lycopus Virginicus and lemon balm tincture to my routine along with vitamin D, B complex and CoQ10. I finally figured out though that the real cure for me was going gluten free and dairy free. No more bloating, no stomach cramps, gas or the big D. Then I found out there is a link between Celiac disease, gluten sensitivity, leaky gut and Thyroid disease. There is a natural graves treatment FB page I am on and a lot of us have cured ourselves of Graves using dietary modifications. I went into remission within 3 months of this diet. I have been normal for over a year now. You really need to be tested for celiac before you start the diet. If you don't have it (it can lead to thyroid disease and then other autoimmune disease when left untreated) then you are sensitive to something you are eating and are most likely dealing with leaky gut. Someday the MDs will catch up with what is really going on here. Our pediatrician is so progressive and knows all this stuff but warned us that a lot of her colleagues are not there yet when it comes to medicine."
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I've just been diagnosed with Graves disease. I am taking Carbimazole 40mg daily now, for 8 days. I have the dreaded 24hr sweats - aching leg muscles - sleeplessness - no energy and lie on bed for most of each day!
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Does that mean that we women are more susceptible to viruses, respiratory infections, etc.? Do most follow a certain diet ?
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Has anyone read or been told by their doc they should "not" take probiotics if they have Hashimoto's or other autoimmune illness?
I read somewhere that one with autoimmune problems should not take probiotics that it could cause systemic yeast infection. Now I can't find that article. Everything else I read states probiotics good for autoimmune disease.
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I have been living with AIH for 14 years, first diagnosed when i was 14 years old. Luckily I am fairly stable with the odd flare up now and again. I am being looked after by the Queen Elizabeth Hospital in Bham and they are brilliant. Currently i'm on 50mg of Azathioprine a day and its brilliant with no side effects. I have been on Prednisolone in the past and i've not got on well with it. My doc keeps mentioning the possibility of me having to go back on it in the future but I don't like the side effects.
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I am 2 days into the vinegar treatment. I can't reach them on my back to use duct tape. Too many anyway. Does anyone out there have them on
their back? Does just the vinegar help?
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I am interested to know if anybody here has autoimmune and if so do you have discomfort in your chest. I've had my heart checked and it's OK but I wake every morning with pressure in my chest. Was wondering if this was typical for autoimmune.
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I have been to multiple doctors over the pas year. I started out at an orthopedic surgeon because my knee was swelling (previous meniscus removal in that knee btw). According to him nothing was wrong with my ligaments so he referred me to a rheumatologist. After testing positive for both blood tests (rheumatoid factor and high anti ccp level) he diagnosed me with rheumatoid arthritis. I did not have any of the typical symptoms of rheumatoid so I went to the Mayo clinic for a second opinion. I then tested negative for the rheumatoid factor and after a thorough exam, he concluded that I don't have rheumatoid. Throughout this time and still now I have been experiencing the following symptoms:-
-random blurred vision
-popping and pain in elbows
-popping in back when taking a deep breath
-numbness every once in a while in fingers
-chest tightness and shortness of breath
I have had chest xrays, full blood work, etc. All came back fine. Am I making this all up in my head?! I feel there is something wrong but every doc I go to says I am fine.
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I'm 25 and over the past 6 years I've been diagnosed with 4 pretty serious autoimmune conditions. When I was 19, I was diagnosed with Rheumatoid Arthritis which is often crippling, even now. I was told this was an autoimmune condition. Shortly after, I was diagnosed with Coeliac Disease, another autoimmune condition. The Arthritis and symptoms of the coeliac disease when I hadn't controlled it obviously made me feel unwell and I often felt lethargic and unhopeful due to a lot of pain and stuff going on in my body.
I managed to go on a clinical trial which allowed me to have a new and powerful arthritis drug which dramatically improved the condition and I managed to cut gluten out of my diet. I also lost a bit of weight - this helped.
However, after the trial, my symptoms of arthritis gradually came back but was usually kept under control with the exception of a few flare ups.
When I was 23, I was diagnosed with Type 1 diabetes after getting a very quick onset flurry of symptoms (another autoimmune condition) - I find this very difficult to manage.
I've recently moved cities and transferring all of my specialists and treatments left me with no arthritis medication, and a long wait until I see a diabetes specialist to adjust insulin levels. As you can probably imagine, I've been in an awful lot of pain and been feeling very down, tired and lethargic. I'm very upbeat although having so many conditions and I don't let it bring me down, even though I work a full-time job 8 til 5 everyday. I've been having problems with blood tests, platelet counts, that kind of thing.
I was aware that I had the antibodies for Hypothyroidism as I had the test for that about a year ago and I knew it was just a matter of time before I developed it. Upon my most recent blood tests, my TSH level was 47.7 - ten times the top end of the normal limit. I've literally just started levothyroxine but, as you can imagine, I feel completely overloaded with health issues and like my head is going to explode and quite down about it all.
I'm sorry to give you my life story but I was just wondering if any one else has any of the other conditions I have and how they manage with all of them?
Also - how should I have been feeling with a TSH of 47.7? Should I have been feeling VERY different because, like I said, I always feel fairly tired and down due to the combination of illnesses. Any advice at all would be appreciated - I feel massively alone with this.
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I'm a 24 year old female. I've been trying to figure out what is wrong with me for years. Two doctors, and two dentists, suggested that I may have an autoimmune disease, but I've had no diagnosis. I am wondering what autoimmune disease in particular this might be closest to. I've had these symptoms for a long time:
- Mild arthritis in right hand (since 17 years old) - maybe once a year, my fingers unexpectedly become swollen and arthritic, and then it goes away after a few weeks. It was most severe a few years ago, when my fingers became very swollen, hot, itchy and red, but it eventually calmed down and has not since returned with the same severity. My fingers in this hand are tilted towards the side, the joints have bended a little a bit sideways. Both of my hands and fingers are always very cold.
- Chronic fatigue
- A skin rash, cluster of small red bumps, that comes and goes on the side of legs. Also get random isolated red bumps throughout the body.
- Underweight and can't easily gain, though this might be genetic. I've always been underweight.
- Hair loss (began at age 18)
- Brain fog
- Vision getting blurrier / sensitive to light
- Eyes sore and red especially in the morning
- Poor looking skin
- Chronic sinusitis for the past 3 years. No cure or known cause (allergies were ruled out) - the sinusitis and red eyes clear up on steroids and antibiotics, but come back afterwards. So possibly a bacterial cause.
- Low blood pressure, low body temperature (96.5 - 97.5 on average)
- Tooth decay. I've had a lot of tooth cavities since I was a teen. I often wonder if tooth decay is the underlying cause of all of my problems. I've had many fillings and a root canal, but continue to have seemingly never ending problems with my teeth. My oral hygiene habits are extremely thorough though, and I try my best to prevent the cavities. I do everything I can to keep my mouth and teeth clean; electric toothbrush, brushing, flossing, special mouthwash, special toothpastes, etc.
I eat a relatively healthy diet and take vitamins and nutritional supplements. I've been experimenting to find the best diet to cope with this..whatever it is. I notice my health and energy levels are very dependent on how well I eat. If I eat junk food, or even the standard American diet, I feel very ill, exhausted and can't function. I can't have "treats" like a cookie or brownie, doing so could make me feel miserable for the next 24 hours. I keep myself semi-functioning by eating as simple and clean of a diet as possible, and consuming a lot of fruit and vegetables every day, along with tea and coffee.
My top two suspicions are that this is all a manifestation of tooth bacteria, or Celiac disease. Or maybe both. Most dentists don't believe that tooth bacteria would cause such an elaborate array of health problems, but I think it might be possible. I've heard of meningitis and heart disease caused by tooth decay. All of my symptoms started after I started to get severe tooth cavities, it was after having a root canal when I began to have severe hair falling out, and from then on my health went downhill. I had a blood test for celiac by a gastrointestinal doctor and they told me the results were negative. I never had an intestinal biopsy.
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I'm sick all the time, flu like symptoms, achy joints, headaches, tired all the time, fatigue.
lab results
Ana titer 1:640 speckled
anti-dna titer 1:20
ra- neg
everything else is neg and normal. What can be wrong with me?
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I am a 20 year old female. for the past 8 months i have had pains in my legs shooting down from my buttocks to my knees in both legs but is worse in my left leg but only while I'm sitting down and after i sit for 10 minutes i start to get pins and needles in my left foot and it is starting to happen more frequently and more painfully as time goes by it makes it hard to drive anywhere and painful to be sitting down. I have had a full spinal MRI and my spine is normal.
i feel like I'm always sick and when i get a cold/flu it never goes away at the moment i have a cough sore throat headaches which i have taken antibiotics for and it went away after 2 weeks of antibiotics but as soon as i stopped taking them it came back even worse. I am constantly yawning and tired.
I had a blood test and my WBC count was low 1.6 but everything else in the test came back normal negative for arthritis. The doctor has said to have another test but he said the low WBC count is most likely just low because of a virus?I have also been loosing hair. It is all making me stressed so the hair loss could be because of that but i don't know are all these symptoms connected? Could the pins and needles and pains be from lupus or another autoimmune disease? i am sick of going to doctors and spending money on MRIs which are useless.
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Jan-12-2014 i had a protected sex with a women, whose HIV Status i don't know. I didn't have any sexual contatcs after that. On June-10-2014 i took HIV Rapid test(result non-reactive).
June-21-2014 I took ANTI HIV 1&2 (ELISA) test in DDC LAL pathlab.
observed value 0.20(range1.0 Non-reactive)
June-26-2014 I tested for all STD's(result-non reactive)
July-10-2014 I tested again for ANTI HIV 1&2(ELISA)
observed value:0.22(Range1.0 Reactive).
AUG-05-2014 I tested again for ANTI HIV 1&2(ELISA)
observed value:0.10(Range1.0 Reactive).
Even Though my 205th day HIV test after exposure is non-reactive, i am still suffering from frequent fatigue,tiredness and IBD.
what are these observed values? does these observed value represents that i have HIV antibodies in small amount? or the HIV antibodies are not yet produces in my case? if not then why am getting these values? can i trust these test results? do i need further testing?
I have consulted two doctors so far. I couldn't get a clear explanation on my results. They always say like 'You are highly unlikely to get HIV'. due to this i got ANXIETY DISORDER. I have been living in fear for the last 3 months and am totally depressed. So please help me to get a clear idea. I just want live normally.
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How does Oraquick work? I know it checks for antibodies and I know there are antigens on the test. My question is how do they create the antigens? Do they create a whole virus and then pull the antigen out of it? Where on the test are these antigens located? Are they on the T line? I have many fears regarding hiv but one of them is this test!
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Can someone please help, my anti-TPO antibodies (range 0-34) have gone from 33.5 in March to 141 in August despite being told to go gluten-free and did so consistently for 3 months? My endocrinologist said going gluten-free would definitely sort the antibodies out. I am on 50mcg T4.
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