Face Swelling - Clobetasol Propionate And Neomycin Sulphate Side Effect?

My mother she is illeterate,she got rashes on cheeks place long back(10 Years back) doctor suggested to use Clobetasol Propionate and Neomycin Sulphate creame for one month  but my mother continued the cream for 10 Years,since last year she stopped to use the cream becuase of doctor suggestion.She is having complications in step wise

1)Pain starts from skin at cheeks place

2)Next Headache

3)Next face swelling

4)Due to the pain she is sleeping 3 days/week

I started diagnose the problem from

1)Neurology(MRI Scan/CT Brain Scan)  all are normal doctor confirmed its not neurolgy problem

2)ENT (CT PNS Coronel & Axiallay view) scan and endoscopy and some other tests  ,allergy tests    she is have minor sinus problem but doctor confirmed that cheeks skin pain/face swelling not coming from ENT Problem  so its not ENT Problem

3)gynecologist    suggested some tests for monopose  even she confirmed cheeks pain and face swelling won't come from Monopause stage.

4)Dental doctor  no issues with root teaths/JAW

RA FactorIgm,ACL Ab also normal.

She doesn't any other complications like BP,Sugar,heart,Liver  this are not from my words i have reports.

I did vitamin   tests for D/B12  she has less D vitamin earler she covered later.

At last  i am   started diagnosing in skin side.