Duloxetine Can Cause Liver Problems?
Jul 26, 2015
I have been prescribed this drug. Is this drug safe as it says it can cause liver problems
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Jul 26, 2015
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Nodular Contour /Heterogeneous Liver Suggest With Normal Liver Labs?
My mother is a 65 year old female, 136 lbs, and on peritoneal dialysis for 3 years due to End Stage Renal Disease. Last week, she began experiencing severe abdominal pain that was a burning/gnawing pain. She went to the hospital and a CT Abdomen was taken without contrast. All was normal.
Over the next four (4) days, the pain persisted, particularly during dialysis exchanges at home. She returned to the hospital who admitted her. Another CT Abdomen was taken at this time which showed "nodular contour on the liver", free air in transverse colon which appeared to be dilated. She was also constipated for several days during this period. The CT impression suggested clinical evaluation for chronic liver disease.
A standard liver panel was taken and all results were normal. Nothing even close to elevated. She has never had a history of any liver issues and never had anything show on a CT for liver. After a day in the hospital, all stomach pain disappeared, she was able to use the restroom, and all stool samples/GI tests were normal without blood. She is naturally anemic due to ESRD with low iron/protein. Her last ANA/autoimmune panel was in December, all clear. No history of any hepatitis.
An Ultrasound Right Upper Quadrant was performed and the impression was no biliary obstruction, moderate ascites (tends to be normal due to peritoneal dialysis fluid), and "heterogeneous liver." The impression suggested referral for cirrhosis evaluation.
She began taking Hydralazine (25mg/3 times daily) in the last 3-4 months. She also takes a host of other blood pressure medicines.
QUESTION: She is currently awaiting a kidney transplant and very worried about this. A blood test will be taken in a couple weeks by a specialist that is supposed to diagnose Cirrhosis. Given this presentation alone, what other causes could explain this imaging results? Should we fear the worst?
Liver Tests :: Echogenic Appearing (non Alcoholic) Fatty Liver
I had an abdominal ultrasound done for some abdominal pain and it was noted in the report as an impression that I had an echogenic appearing liver (such as non alcoholic fatty liver). My doctor at that time didn't tell me and just said my report was normal. When I went in for my Colonoscopy that was unrelated, it was mentioned again and when I did some research I realized what fatty liver actually was. I switched doctors.
My new doctor is considering giving me a CT scan but is checking with the GI department to see if they think its needed, etc. etc. But that there is no treatment for it besides diet modification.
Here's the thing. I don't have any of the risk factors. I am not overweight. I'm actually underweight slightly (BMI is 18, I weigh 110 lbs). I don't drink any alcohol, never did. And I don't have diabetes or hepatitis. The only thing I could do and what I have been doing is change my diet. I stopped eating processed foods, watched my sugar/carbs, and eat more vegetables than I ever have.
I'm a very anxious person and I'm not sure I want to know what the scan says. If it's worse than what I thought, I'm going to be so upset and stressed out. And I can't treat it anyway. It's not like they can give me a medication and make it go away. I think knowing the extent of it will just cause me mental anguish and I'm already stressed out about it as is.
Atorvastatin Causing Liver Damage, But Helps Fatty Liver?
My Cholesterol was 7.8 and I was put on Statins 3 years ago. Because they gave me pains in my legs and other areas I stopped them.
A year ago my Cholesterol was still high and I had changed doctors and was prescribed Atorvastatin 10 mg after 2 months my doctor sent me for blood tests and in a phone call when I was at work he told me that Atorvastatin had caused Liver damage. He said I should stop taking the tablets immediately, pity this advice was not put on my notes so that when I phoned for my blood results a week earlier the receptionist could inform me to stop Atorvastatin. She just said Doctor will be in touch via phone call next week
He referred me to a Liver Specialist.
I went to see Liver Specialist after having Liver Ultrasound. Fatty liver was diagnosed and Liver Specialist promptly put me back on Atorvastatin claiming this would help my fatty liver. I couldn't believe it but what could I do?
Local GP had advised me to have bloods done again after being on tablets for 2 months. When my results came back the Locum doctor I saw said "whoa your Liver is not happy" STOP the tablets and have a blood test in 2 weeks.
2 weeks later Liver levels are coming down so thats a good direction. Dilemma is I have to see my Liver Consultant 16 June 2015. Wish me luck!
Liver :: Weight Loss Surgery To Reduc Fatty Liver
this isn't about me but is about my girlfriend who is about to have gastric sleeve surgery.
She is a 40 year old women that has had a full hysterectomy and has type 2 diabetes. she has had a history of thyroid and weight issues. she is 5,7 weighs 225 LBS. she has an enlarged fatty liver of 27cm and the Doctor said that she needs "emergent" gastric sleeve surgery to bring down her enlarged liver. this was claimed on this past thursday. I have been looking high and low for documentation and statistics on using the surgery for reducing fatty livers but can't find any information. Does this sound right? has there been a history of using this procedure for such cases, I'm worried and scared for her.
Liver Tests :: Possible Fatty Liver With Elevated Enzymes
Been feeling lightheaded and brain foggy and a bit sick recently with some stomach grumbling and pain. Went to the doctors who did repeat blood tests over the course of 8 weeks and have said my enzymes are slightly up which could be the result of mild fatty liver. My question is does this sound related? He's also just tested me for celiac, but told me in the beginning that I could be fighting a virus. I'm worried that the 3 diagnoses he's given are so different I don't know what to believe, also does this mean I should be less worried about the tests because they are low enough to be anything?
View 2 RepliesLiver :: Reactive Hypoglycemia Raises The Liver Enzymes?
I've recently had 2 LFT that both showed raised enzymes, I've had a scan and it shows I have gallstones, however I am currently undergoing investigation into whether I have Reactive Hypoglycaemia, my question is that if I do have RH, would this cause my liver enzymes to elevate?
View 2 RepliesLiver Tests :: How Much Damage Caused By Fatty Liver?
IiIt was picked up by chance thaI have fatty liver, could have had this for years without knowing about it, how do I find out how much damage has been done already if any? My GP does not seem too concerned about it, all my LFT have come back normal so what can I do about it apart from lifestyle change which I'm doing already?
View 13 RepliesLiver Tests :: Reduce Alcohol To Reduce Further Liver Damage
Just before christmas I received a letter from my hospital saying “ recent blood tests show a slightly abnormal liver function and the scan revealed cirrhosis. It is absolutely crucial that you consider urgently reducing your alcohol intake to avoid further liver damage. I would be grateful if you could see your gp to discuss this further.”
Immediately I phoned my gp and couldn’t get an appointment for 2 weeks, when finally seeing my gp she referred me to a councillor, which took another 2 weeks before I saw them, only to be told they don’t have a clue at what stage my cirrhosis is?
Duloxetine :: Not All Bad
I have been on Cymbalta/Duloxetine for over two years now after having reactions to Sertraline etc. This was at 60mg and to be truthful it didn't do a lot. About 8 weeks ago this was doubled to 120 mg and this has increased my movement, mood and power to stay awake. It has also reduced my tremor.
I noticed I seem to be the only person on this level.
I am being queried following abnormal PET scan that indicated possible Parkinson's but DaT scan negative so not that. Also have mild Ischaemic changes in frontal lobes of the brain. All still under investigation. Has anyone else been prescribed this for same or similar problems?
Duloxetine :: Having Headaches
Been on Duloxetine 30mg for 5 days now - having headaches -Will they go away ? - I want to feel myself again any idea how long it takes for the tablets to kick in. I feel ok for a little while in the morning then i feel poorly again have to lay down and take co- codamol to take the headaches away - Can anyone give me any information of their experiences please -
View 1 RepliesFluoxetine To Duloxetine?
I hope you're all making progress and feeling better.
I'll cut a long story short - I was taken off fluoxetine because I went really downhill. My Psychiatrist has given me Duloxetine which is an SSNI. It works on serotonin and nor.....?? I can't remember the spelling.
I'm reluctant to take it right now because I went on the forum for Duloxetine and haven't found many posts at all!! I think there are about 4-5 posts!!
Have any of you had this medication before? Any advice about what I should do? I don't mind the side effects, I'm just worried that my head's going to get messed up further.
Apart from all that, I feel a bit better having posted on here this morning cos I've not been on the forum for a while.
Mirtazapine And Duloxetine
Psychiatrist has upped my mirtazapine from 15mg to 30mg and is about to start me on Duloxetine as a combination, is anyone else in this combo and have any advice?
View 2 RepliesDepression :: Duloxetine And Nightmares
I've been on duloxetine for about 18 months now (I think, my memory's awful) and have always had disturbed dreams and nightmares while I've been on it. Originally I was taking zolpidem 10 mg and Quetiapine 100mg at night but I've taken myself off of those over the last few months. The nightmares have gotten worse though, they're incredibly realistic. Last night I dreamt that I was drinking and I woke up heaving and with an intense headache like I was hungover. Then I managed to go back to sleep and after dreaming that I was back at my parents house and arguing with them, I woke up in such a state and my anxiety was so high I couldn't even move, I was struggling to breathe and scared because I was struggling to differentiate between what was real and what was a dream. I never wake up feeling rested and am constantly tired and yawning throughout the day, I've also been suffering more with headaches. Has anyone else on duloxetine had issues with sleep and dreams and is there anything that helps?
View 2 RepliesExperiencing Bad Duloxetine Withdrawal
just wondered if anyone else is experiencing the hell that is duloxetine withdrawal?
This is my 5th day of being off the duloxetine all together. Im now on Mirtazapine. I dont know if what Im experiencing is the duloxetine withdrawal or the side effects of Mirtazapine :?
I am so spaced out its unreal. I get brain shocks constantly that really take your breath away and literally stop you from doing anything. I go to get dressed and zap, there it is. I bend down to pick up my jeans, and zap. Turn round to look at something and zap. I ache from limb to limb like a 90 year old with arthritis!! Im exhausted physically and mentally and I am just unable to do anything. I haven't been out of the house for 8 days, and haven't got dressed for 6!
I'm so sick of this med roundabout. I've been ill for little over a year now and have sampled 8 delightful anti deps, 3 anti psych and 2 relaxants. I feel like a junkie. Every time I move onto a new tablet, I have to go through some sort of withdrawal. These meds are supposed to be non addictive, but I'm beginning to think otherwise. They said that Valium wasn't addictive when that came out, now look.
I'm just so sick and tired of this whole roller coaster. As if it's not bad enough being depressed and out of your mind with worry and fear in the first place, but to then take tablets that are supposed to help the situation, but actually just add to your problems!
Duloxetine :: Dilated Pupils
Right i decided to wait for stag dos to be finished. Now on day 3 of duloxetine. I have nausea and very tired effects kicking in alongside dilated pupils. Does this subside after time, i never felt this bad on any antidepressants.
View 1 RepliesDepression :: Duloxetine Reviews
Been given duloxetine to to try for my depression and wondered if anybody has been using it what your reviews are on it
View 5 RepliesDuloxetine (Cymbalta) For Pain ? Or Antidepressant?
First of all I am not diabetic but I do need help on the above tablet Duloxetine (Cymbalta) which I believe is given to diabetics for pain relief (or so my doc tells me). I have Cervical spondylosis which gives me extreme pain and for which I take 30 tabs daily plus Morphine and liquid Morphine. Doc has prescribed Duloxetine which is an antidepressant but which I believe also helps pain. Can anyone on this site who is diabetic tell me about Duloxetine or have they taken it and has it helped with pain? I am afraid to start taking it as it does not have good reviews and is used mainly as an antidepressant. There appear to be too many side effects, some of which I have already from morphine and it appears to be difficult to come off. If anyone can comment and help me with this I would be really grateful. I suffer chronic pain 24/7 and my meds at the moment are having little effect on controlling the pain. They just keep increasing morphine dose which I am a little afraid of. Does Duloxetine really work in controlling pain?
View 11 RepliesCymbalta To Generic Duloxetine - Crashed
I have been recently changed from Cymbalta to generic duloxetine. Whilst on Cymbalta, I was able to cut down from 120 mgs daily to 90 mgs daily.
Now I have had to go back to 120 mgs as I have a terrible depressive crash very close to 3 pm every day. I have always taken my full dose in one dose in the morning. Now I am splitting it to avoid the 3 pm crash. I asked my psychiatrist for Cymbalta specifically as in the US it is prescribed for fibromyalgia which I also have. I had seemed to be improving on that front too and was hoping to get back to part time work but I have been more or less bedridden for the last two weeks. Anybody else had problems with the switch over?
Fibromyalgia Syndrome :: Duloxetine Experiences?
i am really struggling with my fibro. The doc has told me to persevere with this tablet. He has also gave me an anti sickness tablet. I would like to know people's experiences with this please.
View 12 RepliesDuloxetine :: Sweating And Yawning Fits
I started on 30mg of duloxetine (cymbalta) about 3 weeks ago. I was prescribed it for severe lower back pain. And mood swings. I was previously on sertraline. But I was getting severe sweats. Constant yawning fits. And feeling hyper. Anyway since being on duloxetine. My sex drive has gone. I have also been having light bleeding for 3 weeks. Has anyone else experienced this. Drs said its a coincidence. But iv never ever had bleeding for more than 5 days. I have stopped taking it for 2 days now. I'm feeling very tired. My back pain is coming back.
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