Cyclizine Reaction :: Terrifying Numbness, Raised Blood Pressure And Racing Heart
Dec 8, 2009
I have just come out of hospital after being treated with IV antibiotics for a Quinsy. One of the antibiotics was making me feel sick so a nice administered cyclizine through the cannula to relieve the sickness. Within seconds, my toes went numb and my head swam and I couldn't see. This progressed to the feeling that my heart was going to burst as it was beating so fast and my head felt as if it was going to pop. Everything was swimming around and I couldn't feel my arms or legs and they wouldn't respond when I tried to move them. My mouth was numb and I was slurring my words. I was terrified! My blood pressure had rocketed and my heart was racing. The panic button was hit and I was quickly given cortisone and antihistamine which began to calm things down. It was a horrible experience. I honestly felt as if I was either going to have a heart attack or a stroke. I'm only 41 and have three small sons. My vision was affected for many hours afterwards, walls billowed and flat surfaces looked as if they were covered in netting. Very disturbing.
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I was on diltiazem (cartia) for several years. It eventually raised my blood sugar level and I was diagnosed with diabetes 2. My blood pressure was not going down, so they took me off diltiazem 240mg, and put me on lisinopril 5mg.
The lisinopril gave me a dry cough, so I was put on losartan 25mg. I asked why not 5 mg and my NP told me because it doesn't come in 5mg....
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My GP recently took me off of venlafaxine slow release from 150mg a day to 0 over the period of 2-3 weeks! This was done due to high blood pressure. I learnt a lot from people on here that it was done too fast, hence the severe withdrawal, so GP put me on mirtazapine 15mg! I've had a severe breakdown, depression back worse than ever, anxiety that I'd never had and self harm that I haven't done since a child, I'm now 48!
New Year's Eve, psychiatrist upped mirt to 30-45mg, yesterday psychiatrist put me back on venlafaxine 150mg and told me to also continue mirt!
On top of that, local GP has doubled my blood pressure tablets and introduced another medication to try and control the blood pressure!
First dose of venlafaxine 75mg last night had me throwing up and, sorry but watery stools!
So now I'm back to square one with 3 different lots of meds on top, shaking and dehydrated, just to name a few! I'm losing the will to fight anymore
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Been on Microgestin now for almost 5 years. I have recently now just developed high blood pressure and am wanting to get off of the pill entirely. Just don't feel normal some days and think It could be the pill. Is it okay to just stop taking the b/c??
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I have a heart rate most of the time from 42 to 50 BPM , my blood pressure is usually 145 to 160 over 75 to 80. My cardiologist has me taking 75 mg, of Lopressor, 360 mg, of verapamil, .4 mg nitroglycerin patch. And now he wants to add 10 mg of Ramipril ( Altace ) a day, my recent cardiograms have have shown sinus bradycardia. That's before starting the Ramipril , I'm just very leary about starting the Ramipril in first of all the highest dose there is, and second of all it could further lower my heart rate and send my heart into an AV Block that could lead to many things not good !
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My 40 year-old wife in recent months has undergone a number of tests following some weight loss. It transpires that she is suffering from hypertension with her 24hr ambulatory readings averaging at 170/110. Further diagnostic tests (ECG, echo and cardiac MRI) were undertaken and her cardiologist told her that her heart is enlarged (moderate) with impaired function (I believe ejection fraction in the region of 45%) but has not been able to identify the root cause of the hypertension. She is asymptomatic and does not have any issues in terms of fatigue, breathlessness, swelling, etc.
She has been prescribed 5mg Amlodipine, 5mg Ramipril and 2.5mg Bisoprolol. The Cardiologist has told her she will be on medication for longevity and that improving the condition will take a long time. Her blood pressure has already come down to 132/84 which the cardiologist was very pleased with. She will be seeing him again in 8/9 weeks with a follow up echo in 4/5 months.
In terms of the diagnosis, the cardiologist has referred only to hypertension but having read and aligned the symptoms of the enlarged heart and impaired function, is it not heart failure.....? Also, what is the prognosis for an enlarged heart caused by hypertension, especially in someone of 40 years of age.....can the enlarged heart and function return to normal over time with the medication?
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I would be interested in your views on whether you believe that there is a relationship between heart rate (at rest) and blood pressure? My bp monitor always gives me my heart rate, which I guess is standard? But I got to thinking (my wife says this is dangerous for me!) why do bp monitors register heart rate unless there was a link to bp? I have "googled" it and can't find anything that is definitive. My resting heart rate hovers around 60 BPM which is quite good apparently. How much attention do you all take of the heart rate readings on your monitors?
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Lately I've been experiencing some concerning symptoms with blood pressure and heart rate. When I get up from either a lying or sitting position, after standing (or walking) for about ten to twenty seconds, I feel very lightheaded and on the verge of fainting. So I grabbed my blood pressure cuff today when this happened to see where I was registering. My BP was 77/57 and my heart rate was 127. And this was just from simply standing up. So I laid back down... And immediately took my BP in the lying position. It went to 149/87 with a heart rate of 75. It changed that much in 30 seconds.
I am currently trying to wean down from Carvedilol.. Was taking 3.125 mg four times daily. After complaining to my cardiologist about nasty side effects (including this drop in BP) he said to cut it in half.
I didn't take the larger dose very long.. Only about a week.
I just wonder if the larger dose could be the culprit.
I have never tolerated the beta blockers well at all. Metoprolol and Atenolol were disasters too.
I'd like to get off BP meds completely, but each time I tried to wean off, my BP would skyrocket.
One thing that is going on right now as well is some serious abdominal pain. Don't know if that's a side effect of Carvedilol or not.
I've had extensive blood work, endoscopy, colonoscopy, abdominal CT, chest xray, many EKGs, and wore a 30 day event monitor.
Virtually all tests were normal.
Here's what did show up though:
Found a small lesion on a parathyroid gland.
Free thyroxine was "slightly" elevated.
Mitral Valve Prolapse with mild regurgitation.
2 very small nodules in lungs (benign according to lung dr)
Some pleural thickening (probably scar tissue from old infection)
Event monitor caught some VT and SVT.
The doctors are telling me these things are insignificant and need no attention.
Family and friends think stress and anxiety are to blame.
But I feel like crap every day. Blood pressure spikes (highest was 210/110)
Heart rate escalates with minimal activity. Night sweats, horrible headaches, severe abdominal pain. Weight loss of 20 pounds in past 6 months. Brain fog and concentration problems.
I've read lots of things that can explain all this:
Dysautonomia
Fibromyalgia
Chronic Fatigue
POTS
Food Intolerance
And of course.. Stress.
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I went in Macmillan hospital for an Iron Infusion, as chronic anemic. I had the iron, and the then administors Cyclizine via IV, i was resting in reclined position on the chair. Suddenly almost not long after maybe 5 mins as if i was either having a heart or stroke, i was struggling to breath serious chest pains,i don't know what my heart rate was since i have Tachycardia, i can say my heart was pounding and chest wall was very fast, i thought i was having a cardiac arrest. Bp from 126 shot up 186/90, i would not speak, my eyes were dialated, my eyes were reported by the nurse as "rolling back in my head", i felt as if paralysed as i could not lift my hands or head, i could not call help. I had tears rolling down my face,it was a few minutes before i could talk. It was the most awful, shocking,distressing,alarming,horrible,frightening experience, to have gone through. To add insult to injury i was sent home, and when i called the Dr acted as if he had never heard of this sort of serious reaction. Not a single note in my after care summary, now covering up. Not a single note about i had no warning about possible side effects, the care has had many failures.
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have been suffering from palpitations every now and then for the past few years but they have been getting a lot worse recently to the point where if I walk up one set of stairs my heart goes berserk and I have to catch my breath once I get to the top. And sometimes just randomly it will feel like it's pounding so hard and fast and nothing I can do to calm it down just wait. I suffer high blood pressure and take medicine. I'm 22 years old. Healthy I'm not overweight. My doctor recently said for me to get a 24 hour heart monitor which I did yesterday and no waiting on the results. Has anyone else had similar symptoms to mine? Or does anyone know what it could be besides anxiety cause I know what anxiety feels like and this is different. It's like my heart just goes crazy sometimes! I'm anxious about the results! If anything was bad they would contact me within a couple of days of receiving the heart monitor right? They say wait up to a week but if urgent will be sooner.
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I am a 41 year old mom of four and a foster son. I was diagnosed with sarcoidosis of the lungs about 10 years ago and soon after began experiencing numerous cardiac symptoms. I experience extra beats, which I have had occasionally since I was about 21, but have also experienced incredible pounding and pressure in my upper belly, chest, neck, and up into my ears. It is similar to feeling like someone turns up the pressure of my blood vessels like turning up a hose or something and you feel every heart beat so strong and powerful. This would happen with any slight exertion (sitting up, standing, trying to walk up a slight incline etc.) My blood pressure and heart rate would rise drastically (once documented in the hospital my bp. went from normal 114/70 to 167/100 and hr. went from 70 to 160s just from standing slowly) My husband, for a while, had to carry me up the stairs because of the pounding and pressure. I would have to do a little bit of exertion and then stop to let the pounding up my throat, neck, head etc. die down some and them take some more steps. or whenever I stood/stand up have to wait for the rush of pounding pressure to lessen and then start to walk. I have been on metoprolol for about three years now to help extra beats and also to control the surge of my bp. and hr. The docs can't figure out why its happening. The meds have helped a little so that I can walk around now but not much more then that. Thing are worse around my period and that's the only pattern I have figured out. The extra beats make me feel like I'm a slave to them . I feel like they control what I do and I don't do. I don't want to leave the house so I won't experience them when I'm away from where I feel the most safe and comfortable(home) My life has changed so much. I use to play volleyball and be active and miss it so much. I stay at home and my family goes to hike. Even when I'm having a better day and Id like to try and do some activity I'm so petrified that I'm going to do too much and something is going to happen. I'm so tired of feeling this way. I feel like I don't have a second that I'm not thinking about my heart and is it going to stop, or should I try to walk up the stairs cause I know that it makes me feel worse and leads to extra beats, pounding etc. I tend to notice that lifting, bending, sitting up from laying down tend to bring on extra beats, but sometimes its just after I sit or lay down. It makes it so hard to just relax cause I'm always wondering when the next one will come and how bad will it be and how bad will it make me feel. I tend to yawn and burp more when I having more pvc's/pac's
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Does anyone experience a rise in blood pressure and heart rate when they stand up or do slight exertion? Also, my heart pounds up into my throat, neck and ears and get extra beats in my heart. I am also very sensitive to adrenaline. Even the smallest things can get my heart pounding. Doctors can't figure it out and there solution is to keep me on a beta blocker (Metoprolol extended release) They have doubled my dose now from 25ml. once a day to 50ml. once a day. I just want to find out why it's happening. It was suggested to me that it possibly could be some form of dysautonomia. I would appreciate any advice I can get.
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Has anyone taken nortriptyline a period of time and decided to stop taking it due to it's side effects with success? The side effects I'm experiencing are increased heart rate, high blood pressure, hair thinning/loss and muscle twitchings/spasms.
Brief story about me: I was never a headache person or a migraineur. I only got these headaches after a lumbar puncture 7 months ago. Needless to say, it has changed my life as I am having headaches 50-100 times a day. I'm currently taking 10-20 mg nortriptyline to keep the intensity down, but the side effects is giving me a lot of problems (increased heart rate and hair thinning/loss are my biggest problems). I'd like to hear from anyone who has a similar story to mine.
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I am a 60 year old women that ran for over 45 years and I always had a low heart rate and blood pressure around 110/70. Lately my heart rate is as low as 43 and my blood pressure is either low or semi-hi. My blood pressure can be as low as 93/53 or as high as 130/90 and the heart rate can climb up to 110 only when climbing the stairs or squatting down, I normally would not worry about this but I am getting a lot of lightheadedness, (on the verge of passing out) and sometimes I have a balance problem with the lightheadedness but not all the time. I haven't ran for about 20 months due to the balance problem and lightheadedness.
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26 yr old female. Blood pressure is 120/80 exactly with a heart rate of 73. But I suffer daily with chest pains all over the place and back and neck pain. Everyday...panic related? Over exaggerated? Are my readings normal? Should I worry about the pains in my chest with this kind of reading? Also...as you can tell my mind races. Feeling so exhausted and very alone.
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My anxiety has been terrible since peri menopause started about 8 years ago.I am 46 now and the heart palpitations and increased blood pressure is getting to me. I had blood work,had a holiter monitor test for 48 hours and the results were normal.My anxiety is horrible which in turn makes everything else go up, can this really be normal?
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I'm 9 weeks pregnant, and today was admitted to hospital with severe morning sickness and dehydration. I was in a&e, and at this point, sick, tired, but generally in good spirits, no anxiety, and to be honest, pleased about being given fluids at last!
I was then given a dose of Cyclizine in my IV, I'm not sure what dose it was. Literally as soon as it went in, I immediately had a very strong urge to vomit, which I managed to fight off. I started to shake uncontrollably, and felt very 'woozy'. The nurse didn't even give me the whole dose, he decided to stop at the point. He then left, and my boyfriend had to call him back in. I went as white as a sheet (according to the boyfriend), was still shaking uncontrollably, the nurse did my obs, and my heart rate was about 150 bpm. I became extremely anxious, with a feeling of impending doom. I was apparently not acting 'normally' for me and not speaking properly. I tried to get up, but my whole body felt extremely heavy.
For me, the whole episode felt to last a long time, but my boyfriend states that it lasted no longer than 10 minutes. The shakes took an hour to wear off completely, and the heaviness, at least 3 hours. This evening (12 hours on), I still feel anxious and 'not quite right'.
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I am experiencing acute insomnia. Is this familiar to any other users of this medication?
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After reading all these posts about Cyclizine, I feel I should add my own traumatic experience from 7 years ago:
(I now know that I am severely allergic to Cyclizine).
Back in the ward after breast cancer surgery with two visitors at my bedside, I suddenly began to feel nauseous. Unable to move my head at the time, I asked a number of times if I could have a 'sick bowl' handy as I felt I was going to be sick. No-one seemed to hear my plea, even though there were lots of medical staff and visitors around in this busy ward. I felt I was speaking loudly but my request still went unanswered. I summoned up the strength to really shout out Please, I need a sick bowl - I think I'm going to be sick. Next thing I saw the nurse half way down the bed putting a needle into the back of my right hand. I asked her what it was for and she replied "Just something to stop you feeling sick". Within seconds of that a strong wave of something went through my head and through every part of me. I started to feel as though my whole body was like jelly and (just as one other poster has described) felt as though I was drowning, couldn't breathe and literally felt as though the life was rapidly draining out of me.
Although I couldn't move my head (or any part of my body), I could see just in front of me and was aware that the woman in the bed opposite me was sitting up and staring at me, as was her visitor. I wanted to shout out Stop Staring at Me, What are you looking at .... but the words wouldn't come out.
There was a rush of panic all around my bed, with doctors having been called and nurses running around but at this stage I couldn't see what was going on - only hear. I heard to my left what I recognised to be the Sister's voice (from having spoken with her earlier) - shouting angrily "Who turned this off?" She was obviously referring to whatever machine I had been attached to there - which had apparently turned itself off!
Then I remember another nurse's voice which I recognized very clearly as an American nurse that I had been chatting and joking with earlier. Although I couldn't see her, I knew it was her because I recognized her loud Texan drawl. She was also the nurse who I had seen (with my tunnel vision) put the needle into my hand. I do believe now that it was her voice that saved my life. Her voice was all I could hear at this stage. She was obviously very close right in front of my face and I remember she kept repeating abruptly and loud: "Don't close your eyes - KEEP YOUR EYES OPEN!" My eyes felt so very very heavy and they kept closing. I so badly wanted to keep them closed - but then her loud voice would bark out the order again "OPEN YOUR EYES!" and with all the strength I could muster I forced them to open each time. It was very hard to do, like I needed a bulldozer to get them to open ... but I managed to do so, only because I could tell from the urgency in her voice that I HAD TO keep those eyes open.
I was also aware that I had been given an oxygen mask and at this stage must have been coming around. The "jelly" feeling had gone and I remember feeling my nose was itchy under the mask. I wanted to scratch it but couldn't move my hands. I'm not sure how long all this was going on, but when the panic was all over I remember the Sister then telling me that I should add 'CYCLIZINE' to my list of allergies. (I am also allergic to Penicillin (as well as some other antibiotics), and this is something I already knew).
I'm not sure that CYCLIZINE should be banned altogether, as it is obviously something that is helpful to others (in the same way as Penicillin is to others), but I do think it should come under the same category as Penicillin and perhaps some sort of pre-test should be done before administering the drug.
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I was in hospital in 2006 with severe illness. I had gotten up to go to the bathroom yet collapsed on the way there. I was given morphine as I was in extreme pain, however, i began feeling very sick, so cyclizine was put straight into my drip. Literally 20 seconds later, i remember feeling as if someone had put their hands round my neck - I couldn't breathe and my heart was racing - this is the last thing i remember. According to my mother and father, I went into cardiac arrest - blacked out, and then was unconscious. At this point, I was dead. I had no pulse and was not breathing. I was given emergency CPR and was thankfully, revived. I remained in hospital for the next week under strict observation. I was 15 at the time. I have a severe allergy to cyclizine, and never again will I go through this ordeal.
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Cyclizine is dangerous and I will not stop warning people of the awful reaction to the drug company to own up their responsibility. I cannot do this alone, I need all your help we have to warn people of the danger of taking cyclizine.
Positive feedback on this?
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