Arthritis :: Ringing In The Ears With Hydroxychloroquine


Apr 22, 2015

I was diagnosed with OA in my lumbar & cervical spine 10+ years ago although it has not caused me any severe problems. I am now in a new state & under the care of a new rheumatologist. She has diagnosed me with Sjogren's & also "probable lupus" (I have many of the symptoms but nothing has shown up in blood tests as of yet.)

Over the past few months my knuckles have gotten bigger so that I cannot put on rings or remove my wedding band. My fingers also swell, & there are some nodules on the knuckles of 2 fingers up near the fingernails. My rheumatologist told me I now have RA.

I have been taking prednisone bursts every now & then to help with my problems. I have also taken it for several weeks at a time, either 10 mg/day or 5 mg/day. Most recently I had been taking 5 mg/day but it was not helping me. I asked at my last appointment about bumping it up to 10 mg/day again, but she is not wanting to do that. I don't know if its just this state I'm living in or what, but every medical professional I see tells me that taking prednisone long term is not good ... yet I know of people elsewhere who have been taking it for many years.

Three weeks ago my rheumatologist asked me to try hydroxychloroquine while I tapered off the prednisone. Not long after I started taking this medication, I noticed I was having ringing in my ears. I really didn't pay much attention to it ... figured it was just some fluke thing. I never had ringing in my ears prior to starting the hydroxychloroquine. As time went on the ringing got worse. I checked the side effect sheet that came with the medication & ringing in the ears was listed as an "unlikely but serious side effect" & it was noted that if this occurred I should "notify my doctor immediately."

I called my dermatologist's office & unfortunately her nurse took the call. This nurse seems to feel that she is a doctor. She has given me incorrect instructions in the past regarding medication. When I told her what was happening, she told me to stop taking the hydroxychloroquine for one week, then to start taking it again ... "just to see that there's nothing else that could be causing the ringing."

If the ringing hadn't been happening prior to me taking the medication, & it stopped immediately after I stopped taking it, then why do I need to start taking the medication again? Again, this ringing is described as an "unlikely but serious side effect." I am concerned that starting to take it again may result in irreparable harm to my hearing.

Am I just being silly/overcautious? Has anyone had this experience or a similar one?

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On June 9th I got some kind of stomach flu or food poisoning.  I had severe vomiting and diarrhea.  Other than a canker sore under my tongue, I was starting to feel better.  I was exercising again and working again.

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So far I've seen one ENT, but other appts are coming for neurologist and another ENT.  My hearing test was perfect.  The ENG/caloric test came out normal, which surprised me.  He suggested I might have Mal de Debarquement Syndrome.

I became became imprisoned in my home, and I started to feel physically weak as the days went on.  After learning about vestibular exercises on the Internet, I decided to start doing them on my own.  They seem to have helped with my balance and with my eye-darting issues.  I now go for very long walks. I am starting to drive again too.  However, everything feels totally different than it did before this all began.

There were a couple of nights where my brain was doing odd things. I got hot flashes (even though I'm a guy) and heart palpitations in the middle of the night one time.

My persistent systems right now are:

-susceptible to dizziness when on the computer, watching TV, doing quick head turns, being inside stores

-high-pitch ringing in my left ear

-fullness in my right ears that comes and goes, almost like there is fluid in them

-harder to concentrate

-unsteadiness as I move.  Sometimes it's a "bobble"; other times it's like I'm leaning in one direction or another.  Sometimes it's almost normal.

-sensitivity to sound, like the bath water running

-misidentification of sounds.  I sometimes think the garbage truck is outside, only to figure out it's our air conditioner.

Let me know what you think.  I would like to begin living a normal life again: return to work, use a computer and watch TV normally, be able to drive long distances without worry.  I'm thinking it's VN, but I did not have an "acute" spinning phase, plus the caloric test was normal.  The canker sore may be relevant because I've read that the herpes virus can attack the nerve.  

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the Rheumy nurse has told me to try it again to make sure it was the cause. Thing is, I've had Sjogrens for about 20 years with the usual dryness, but I cope with eye drops and vaginal lubrication and HRT cream. Apart from the odd tummy troubles, I'm thankfully not in pain and lead a pretty normal life.

i'm not at all sure if taking hydroxychloroquine is worth it for me, as I dread it damaging my eyesight. My Specialist seems to think it may help with my poor sense of taste and smell, which would be great as it's depressing. 

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