Cymbalta (Duloxetine) :: Severe Hand Tremors
Nov 1, 2015
Has anyone had this happen? I had gone up from the 20mg dose to the 40mg dose and was doing better. Less depression and the goal was to ease my fibro pain (I currently take Gabapentin and Tramadol) and eventually stop taking Tramadol. I suddenly started shaking. I had muscle jumps (can't think of another way to describe it) in my legs and I literally shook so bad I couldn't turn pages on my Kindle without trying a few times. It was disturbing.
The doctor called me back said to go back to the 20mb dose. I continued to shake...but it lessened. I am now going off it by taking it every other day (20mb) and can't get the Dr. to return my call.
I have tried all the Fibro drugs. Lyrica didn't work. Savella caused bad rapid h/b. Effexor caused muscle jumps in my legs too (but not hand shaking).
If I continued to take it would the hand tremors go away? No one can answer that. Pain is worse since I have eased off so it was actually working. I want to continue if it will lesson, but I don't know if it will.
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First of all I am not diabetic but I do need help on the above tablet Duloxetine (Cymbalta) which I believe is given to diabetics for pain relief (or so my doc tells me). I have Cervical spondylosis which gives me extreme pain and for which I take 30 tabs daily plus Morphine and liquid Morphine. Doc has prescribed Duloxetine which is an antidepressant but which I believe also helps pain. Can anyone on this site who is diabetic tell me about Duloxetine or have they taken it and has it helped with pain? I am afraid to start taking it as it does not have good reviews and is used mainly as an antidepressant. There appear to be too many side effects, some of which I have already from morphine and it appears to be difficult to come off. If anyone can comment and help me with this I would be really grateful. I suffer chronic pain 24/7 and my meds at the moment are having little effect on controlling the pain. They just keep increasing morphine dose which I am a little afraid of. Does Duloxetine really work in controlling pain?
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I have been recently changed from Cymbalta to generic duloxetine. Whilst on Cymbalta, I was able to cut down from 120 mgs daily to 90 mgs daily.
Now I have had to go back to 120 mgs as I have a terrible depressive crash very close to 3 pm every day. I have always taken my full dose in one dose in the morning. Now I am splitting it to avoid the 3 pm crash. I asked my psychiatrist for Cymbalta specifically as in the US it is prescribed for fibromyalgia which I also have. I had seemed to be improving on that front too and was hoping to get back to part time work but I have been more or less bedridden for the last two weeks. Anybody else had problems with the switch over?
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I had a very successful pain clinic appointment yesterday, by successful I mean i saw a Dr who wasn't a complete arrogant idiot, he was very nice and tried to think out of the box a little. I asked him for lidocaine patches and although he said he did not think they would work because of the pain being deep he was willing for me to try them, he couldn't prescribe them so he's written to my GP, he also suggested capsaicin cream and finally he thinks i should try cymbalta/duloxetine. I explained that id tried various anticonvulsants and hated them due to side effects and that i was not depressed (i probably should be) but i'm not, i get angry more than sad for the chronic situation but i don't feel hopeless and apart from super hellish days i cope fairly well.
The thing is my little boy is my world, i'm so concerned taking an antidepressant when i don't feel depressed will kick off depression, especially if they don't work and i come off. I used to suffer with depression when i was younger and i know how horrible it is and when your i was in that cycle nothing or no one mattered anymore so i'm concerned as i'd rather continue to live in daily pain knowing my son is getting the "real" me than be on any meds that might change how i feel or how i am towards him.
Does anyone have experience with these specific meds? Especially taking them for just pain and not depression?
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I didn't do well on cymbalta (duloxetine). Initially, I started to feel better, but after a couple of months I started to feel depressed again. I also gained weight.
When I started to withdraw from cymbalta, my weight started to creep up even more. I've always been 7 st, and now I'm 8 st and 5 lbs.
My Psychiatrist wants to start me on venlafaxine, but I'm so worried that I'm going to end up gaining more weight. In the past, I've been on Citalopram and Fluoxetine. None of those worked for me, that's why my Psychiatrist tried the SNRI.
I feel like a complete failure, and am believing I'm unhelpable. Weight gain is a big issue for me, I don't like not being in control.
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I'm seeing a neurologist next week because of the above symptoms. I'm a 68 year old woman and my GP said it's the way my body is aging! I'm not so much worried (about for example Parkinson's) as intrigued. I know lots of people suffer hand and finger tremors but I am a bit unnerved by my hands and fingers moving very, very slowly on their own. As I stop typing for a moment my right little finger has raised itself from the keyboard as if it were being pulled but very very slowly. My whole hand will slowly curl and even my arms will move on their own if I am "at rest". It's probably something with no explanation but I wonder if anybody else who has been diagnosed with a neurological/muscular condition has experienced this symptom. I do feel as if I am trembling right through my body and my feet will also move independently if I keep still long enough. I don't seem to have any other Parkinson's symptoms.
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I recently asked advice as changed to duloxetine from sertraline. I am experiencing severe RAGE since changing my medication and don't know what to do about this! Have any of you suffered with severe rage, I have tried many antidepressants over the years but have not experienced anything like this! Feeling really upset and desperate now, also has done nothing to help with my depression in fact it is worse than ever.
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I noticed tremors on my body since I was 12. But it was mild tremors that I didn't care about. But since November 2014 my tremors got worse and now I have tremors all over my body. For example, when I try to do abs my trunk starts to tremble, when I lift my legs against the gravity, they start to tremble a lot, when I try to smile my face trembles, when I'm with my friends and try to drink some tea from a tea cup my hand and my head starts to tremble, and I feel that my neck and my head will start to tremble if I move in a "No" movement, and sometimes when I am in a place with lots of people my legs starts to shake and I get very embarrassed about that and they start to shake even more. So I went to a neurologist and I showed to him the positions that I tremble and my situation, and he said that some people has more physiologic tremor than others (even though I think that I have essential tremor), and he had to give me something for the anxiety, but I tremble a lot, and when I'm cold my body trembles a lot (a lot more than normal people). He gave me Inderal 10 mg to take 3 times a day . But it's not working on controlling my anxiety. I also tried to take 20mg and it didn't work as well and I'm not having side effects too. But the problem is I get anxious because of my tremors and not the opposite . If I had no tremors, I wouldn't have a reason to be anxious. I already went to the only 2 neurologists that I have on my city and only the second one gave me some medication. I really want this tremors to stop. I know he gave me that dosage because the anxiety makes the tremors worse but not even for the anxiety it's working. And I'm going to work out of my country with people that I don't talk and I will get very embarrassed with this tremors... So what should I do?
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I have only been on Gabapentin for 6 wks. 100 mg. 1 x day. Do I need to taper off. From what I read, I don't want to continue or increase it. I have essential tremors and they have been a lot worse. Also, I have extreme fatigue.
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been on lexapro which hasn't helped zoloft and effexor too just wondering if paxil or cymbalta works for anyone please help i have severe anxiety depression panic
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Has anyone heard of b12 injections to get off Cymbalta? I have been on for 3 years and can't get off this drug. The withdrawal is horrible. the spins, sweats and other stuff is a killer. I am down to my last 30mg pill and will try to take some of the stuff out like suggested but does anyone have any vitamin help on this?? I am going to read the the B12 epidemic book but have yet to hear of anyone that this has helped.
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I suffered severe depression and anxiety and began to get bad tremors around 6 months ago, this was a first for me. My psychiatrist and GP thought it was because I was taking Sodium Valproate which is a mood stabiliser, however I have now come off that (still taking antidepressants, 80mg Lovan daily) but I still have the tremors.
My GP suggested Parkinson's but that I shouldn't have the brain scan now because medicare are not covering them.
Could anyone give me their thoughts on what I should look for in Parkinson's other than the tremors?
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The only way to get through this "transition" in the best possible way is to stay informed as to what is going on with our bodies. Being as though every woman is different, what may work for one may not work for the other. But knowledge is key to being able to live our lives the best and healthiest way possible.
With that being said, I came across some information on the internal shaking and jitters. Now this info may not apply to you, but if if does, by all means take it and do more research on your own to help yourself. Some of the first symptoms that I experienced that started to really ramp up anxiety for me is the racing heart and the internal shaking. I felt the the shaking in my chest and stomach mainly, but I could feel it all over. At times I would get the racing heart with it.
The shakiness and jitters first. We already know that the decline in estradiol can affect blood sugars, and digestive issues. For some the shakiness and jitters can be due to the blood sugars and dietary changes can help to stable that during peri/meno if you are not a true diabetic. It can also be due to anxiety and adrenaline surges. The other possibility can be digestive related. Since the digestive system is affected by declining hormones we digest food slower and have more gas than we usually do as well as an excess of stomach acid. I since have been diagnosed with GERD as many women do in peri/meno and I do have excessive gas and stomach acid which causes that burning feeling. For me what has been causing that internal shaky feeling in my chest and stomach is stomach acid putting pressure behind the breast bone which irritates the vagus nerve that can cause the anxiety type symptoms. If I chew a tums or take an acid reflux tablet the internal shakiness and jitters stop. Drinking chamomile tea, ginger capsules or tea, tums, rolaids, omeprazole, zantac, cal/mags or whatever you choose to use calms the stomach acid, calms the vagus nerve and neutralizes excess gas. Also when the vagus nerve is irritated it can cause heart palps and that is why when your reflux is acting up the excess acid pushing the vagus nerve can start palps. Now again this may not be the case for all, but it may be for some. So I thought that I would share the info just in case it may help you.
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I was prescribe gabapentin and on day one I has blurred vision and felt like someone was sitting on my chest it was hard to breath I gelt winded and anxious now day three and its getting worse I had my pulse and oxygen level checked it was 97 pulse and 10 oxygen level this time I was feeling tremors, winded, heaviness to my chest, blurred vision, extremely dizzy (I actually feel), numbness and tingling in my hands and feet...
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My Two Cents Worth:
First of all I would like to say a heartfelt thank you to everyone who has written about their experience of being on Cymbalta and their struggle
with Cymbalta withdrawal. I believe that you have saved not only myself but many others from a lot of pain.
I was prescribed Cymbalta 30mg on the 16 April 2012 by my doctor in order to treat depression and anxiety. I was told to 'try it' over the next 7 days to see if I could handle the side effects. He said that in the beginning I would get some nausea but that I should persevere and try to stay on it for at
least a month, which is when it would start to work. He never said anything about it possibly damaging my liver or anything about withdrawal symptoms, just that I shouldn't suddenly stop in the middle of the treatment.
I was nervous about taking it but at the time I was desperate for any kind of help. I took one 30mg capsule about 12pm with some lunch (to minimise the nausea) but by 2pm I had a very upset stomach with a lot of wind (gas), slight cramping, a very stiff neck, dry mouth and headache.
Around 4pm I fell asleep (without meaning to) while on the couch. I woke up a couple of hours later feeling completely disorientated, confused and nauseous. I felt so spaced out and like I was still dreaming.
By 7pm I had such bad nausea I couldn't make dinner (much less eat anything) and a very bad headache.
I was drinking heaps of water to help with the dry mouth and I also had very bad constipation (something I have to avoid as I have diverticulitis).
The next day (17th April) I felt a lot better (more clear-headed) and decided to Google Cymbalta to find out more about the side effects and if people had experienced the same effects as I had. I became so scared when I read all the forums and support groups for people battling with horrific Cymbalta withdrawal, I decided to quit it then and there.
I decided to go cold turkey simply because I had only taken one capsule and reasoned that it wouldn't have had much effect on me yet. I didn't really want to take a half capsule as I didn't want my body getting used to having the drug in my system anymore than it already had.
The rest of the day I was anxious, shaky and had bad diarrhoea. By bedtime I was headachy (pressure at the back of the head) and with a little neck pain.
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Symptoms starting from 10 years ago(puberty, I'm 22 now)
FULL body joint pain.
FULL body muscle pain and spams.
severe muscle and tendon cramps
randomly nauseated.
IBS
random severe constipation
purge and splurge eating habits.
insomnia
Migraines lasting for days.
muscle weakness.
muscle atrophy
uterine, bladder and rectum prolapse (they said this is because my muscle spasms are so severe in my pelvis it just couldn't do its job holding the uterus suspended.)
Hot flashes
heat rashes
swollen lymph nodes
all symptoms of raynaud's disease.
overly dry tight skin.
all day fatigue
neuropathy
vertigo
major depressive
general anxiety
memory loss
extremely hard to concentrate.
sharp rib/lung pain? when breathing randomly.
spinal pain.
sciatica
--this is all I can think of with my current migraine eating away at me.
test results so far:
Ana tested 3 times over 9 months- 1:1280 homogeneous. 1:1280 speckled. 1:1280 homogeneous
HGB and HCT juuuust under normal levels.
ESR - 11 after just getting off prednisone, 20 4 weeks later. range was 0-20
Calcium level- just below normal
Total protein and albumin level- cusp of low, going down from medium normal range over 6 months
ALT-SGPT - just below normal
trace to moderate blood and leukocytes in urine
small amount wbc and rbc in urine
Promtime just below normal
Negative for RNP, SM, SS-A AB, SSB/LA, SCL 70, DS DNA.
CCP- range is 0-19, I had 20 the first test, and 4 months later it was 35.
now here is my problem. my rheumatologist and PCP are ignoring the Ana. so they said I have Fibromyalgia. but from everything ive read 1:1280 is highly unlikely to be a healthy positive.
they won't diagnose RA because while I was positive for ccp is a "mild positive" and I didn't have inflammation showing in my blood work.
they've had me on celexa, Zoloft, amitriptyline, hydroxyzine, ambien, Cymbalta, gabapentin, flexeril, Percocet(after delivering) and every OTC they recommended. I've been to physical therapy, pelvic floor therapy, and chiropractic.
NOTHING HAS HELPED.
What am I missing? should I get a knew Rheum? any ideas whats going on really? any ideas on what can help?
I'm exhausted, physically, mentally, emotionally.
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I was prescribed cyclizine tablets for vomiting and nausea. I was admitted into hospital for a week in 2014 suffering side effects from taking Cyclizine. I am still suffering side effects.
Below are some of my side-effects:
Chorea, tremors, affecting the head, hands, feet and face
neurological disorder characterized by jerky involuntary movements
disorientation, speech problem, blurred vision, hearing problem,
breathing problem and loss of balance.
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Hi recently I had massage and handjob where masseuse was clearly bleeding in her finger, it was a fresh cut and I had a very fresh cut on my penis mucous membrane. After finishing the hand job I saw little blood on my penis which had come in contact from the who gave massage. There was a clear blood fresh blood that had gotten into contact with the open wound I had in my penis. Now I'm terrified because she had a fresh blood from her hand and which clearly came in contact with my very fresh open wound which can give direct access to my bloodstream. I'm worried now because of this because it was a fresh blood, fresh cut and I did see some blood in my penis which was exactly on top of my wound. Did I put myself in to risk. I'm trying to contact her but she has switched off her mobile. No sex no kiss was involved.
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I have been on Cymbalta/Duloxetine for over two years now after having reactions to Sertraline etc. This was at 60mg and to be truthful it didn't do a lot. About 8 weeks ago this was doubled to 120 mg and this has increased my movement, mood and power to stay awake. It has also reduced my tremor.
I noticed I seem to be the only person on this level.
I am being queried following abnormal PET scan that indicated possible Parkinson's but DaT scan negative so not that. Also have mild Ischaemic changes in frontal lobes of the brain. All still under investigation. Has anyone else been prescribed this for same or similar problems?
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Been on Duloxetine 30mg for 5 days now - having headaches -Will they go away ? - I want to feel myself again any idea how long it takes for the tablets to kick in. I feel ok for a little while in the morning then i feel poorly again have to lay down and take co- codamol to take the headaches away - Can anyone give me any information of their experiences please -
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I hope you're all making progress and feeling better.
I'll cut a long story short - I was taken off fluoxetine because I went really downhill. My Psychiatrist has given me Duloxetine which is an SSNI. It works on serotonin and nor.....?? I can't remember the spelling.
I'm reluctant to take it right now because I went on the forum for Duloxetine and haven't found many posts at all!! I think there are about 4-5 posts!!
Have any of you had this medication before? Any advice about what I should do? I don't mind the side effects, I'm just worried that my head's going to get messed up further.
Apart from all that, I feel a bit better having posted on here this morning cos I've not been on the forum for a while.
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